Unsupervised 3D Prostate Segmentation Based on Diffusion-Weighted Imaging MRI Using Active Contour Models with a Shape Prior

Xin Liu; Haider, Masoom A.; Yetik, Imam Samil
January 2011
Journal of Electrical & Computer Engineering;2011, p1
Academic Journal
Accurate estimation of the prostate location and volume from in vivo images plays a crucial role in various clinical applications. Recently, magnetic resonance imaging (MRI) is proposed as a promising modality to detect and monitor prostate-related diseases. In this paper, we propose an unsupervised algorithm to segment prostate with 3D apparent diffusion coefficient (ADC) images derived from diffusion-weighted imaging (DWI) MRI without the need of a training dataset, whereas previous methods for this purpose require training datasets. We first apply a coarse segmentation to extract the shape information. Then, the shape prior is incorporated into the active contour model. Finally, morphological operations are applied to refine the segmentation results. We apply our method to an MR dataset obtained from three patients and provide segmentation results obtained by our method and an expert. Our experimental results show that the performance of the proposed method is quite successful


Related Articles

  • Clinical impact of diffusion tensor imaging. Tanenbaum, Lawrence N. // Applied Radiology;Jan2007 Supplement, Vol. 36, p12 

    The article focuses on the clinical impact of diffusion tensor imaging (DTI). In the late 1980s, the clinical use of diffusion magnetic resonance (MR) had revolutionized the MR imaging of patients with suspected brain infarction. Based on several case studies, it has been found that advanced...

  • DIFFUSION TENSOR IMAGING. TATUM IV, WILLIAM O.; KAPLAN, PETER W.; JALLON, PIERRE // Epilepsy A to Z: A Concise Encyclopedia;2009, p96 

    An encyclopedia entry for "diffusion tensor imaging (DTI)" is presented. It states that DTI is more sensitive to white matter injury than conventional brain magnetic resonance (MR) imaging. It notes that this imaging technique also reflects the myelin integrity in vivo and the inherent...

  • Basic concepts of advanced MRI techniques. Pagani, Elisabetta; Bizzi, Alberto; Di Salle, Francesco; De Stefano, Nicola; Filippi, Massimo // Neurological Sciences;Oct2008 Supplement 3, Vol. 29, p290 

    An overview is given of magnetic resonance (MR) techniques sensitized to diffusion, flow, magnetization transfer effect, and local field inhomogeneities induced by physiological changes, that can be viewed, in the clinical practice, as advanced because of their challenging implementation and...

  • Diffusion tensor imaging of the superior cerebellar peduncle. Battal, Bilal; Hamcan, Salih; Akgun, Veysel // Child's Nervous System;Dec2013, Vol. 29 Issue 12, p2143 

    A letter to the editor is presented in response to the article related with diffusion tensor imaging.

  • Diffusion Tensor Imaging (DTI) - A New Imaging Technique Applyed in Multiple Sclerosis. ROCEANU, Adina; ONU, Mihaela; ANTOCHI, Florina; BAJENARU, Ovidiu // Romanian Journal of Medical Practice;2012, Vol. 7 Issue 4, p355 

    The article discusses the use of diffusion tensor imaging (DTI) technique to study the white matter architecture and integrity of the normal and diseased brains such as multiple sclerosis and stroke. The physical principles of the DTI magnetic resonance imaging (MRI)-based technique are...

  • Data quality in diffusion tensor imaging studies of the preterm brain: a systematic review. Pieterman, Kay; Plaisier, Annemarie; Govaert, Paul; Leemans, Alexander; Lequin, Maarten; Dudink, Jeroen // Pediatric Radiology;Aug2015, Vol. 45 Issue 9, p1372 

    Background: To study early neurodevelopment in preterm infants, evaluation of brain maturation and injury is increasingly performed using diffusion tensor imaging, for which the reliability of underlying data is paramount. Objective: To review the literature to evaluate acquisition and...

  • Analyzing functional, structural, and anatomical correlation of hemispheric language lateralization in healthy subjects using functional MRI, diffusion tensor imaging, and voxel-based morphometry. James, Jija S.; Kumari, Sheela R.; Sreedharan, Ruma Madhu; Thomas, Bejoy; Radhkrishnan, Ashalatha; Kesavadas, Chandrasekharan // Neurology India;Jan/Feb2015, Vol. 63 Issue 1, p49 

    Context: To evaluate the efficacy of diffusion fiber tractography (DFT) and voxel-based morphometry (VBM) for lateralizing language in comparison with functional magnetic resonance imaging (fMRI) to noninvasively assess hemispheric language lateralization in normal healthy volunteers. Aims: The...

  • Diffusion MR Imaging of the Brain in Patients with Cancer. Debnam, J. Matthew; Schellingerhout, Dawid // International Journal of Molecular Imaging;2011, p1 

    Over the last several years, there has been significant advancement in the molecular characterization of intracranial diseases, particularly cerebral neoplasms. While nuclear medicine technology, including PET/CT, has been at the foreground of exploration, new MR imaging techniques, specifically...

  • MR and Diffusion Tensor Imaging of Vein of Galen Aneurysmal Malformation in an Infant Presenting with Spastic Diplegia and Seizures: A Case Report. Summa, A.; Ormitti, F.; Crisi, G.; Ventura, E.; Cerasti, D. // Neuroradiology Journal;Feb2010, Vol. 23 Issue 1, p114 

    A three-year-old girl developed spastic diplegia to the right and irregular tonc-clonic movements. Phenobarbital was started because of suspected seizure activity. The Pediatric unit asked for brain MR imaging to investigate neurological symptoms. MR and diffusion tensor imaging showed a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics