Hla-G Ve Kanser Ä°liÅŸkisi

May 2012
Duzce Medical Journal;2012, Vol. 14 Issue 2, p70
Academic Journal
The importance of HLA antigens on immunity and tissue compatibility is known. The suppressor role of a non classical HLA antigen HLA-G is being clearer with the results of last studies. On normal situations its being is restricted in a few type of tissue. It can be found on fetal tissues like trophoblasts, tymic medulla, cornea, pancreatic islets and precursors of erithroid and endothelial cells. The expression of HLA-g is increased in the situations like malignities, transplantation, multiple sclerosis, inflammatory diseases and viral infections. In this review it is aimed to give short information on HLA system and to introduce the studies pronouncing the relation of HLA-G and malignities.


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