TITLE

Systemic lupus erythematosus complicating autoimmune pulmonary alveolar proteinosis that was worsened by immunosuppressive therapy

AUTHOR(S)
Nagasawa, J; Kurasawa, K; Maezawa, R; Owada, T; Hanaoka, R; Fukuda, T
PUB. DATE
September 2013
SOURCE
Lupus;Sep2013, Vol. 22 Issue 10, p1060
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A 26-year-old Japanese woman developed autoimmune pulmonary alveolar proteinosis (PAP) during glucocorticoid therapy for systemic lupus erythematosus (SLE). Intensive immunosuppressive therapy worsened the PAP. De-escalation of immunosuppressive therapy improved the PAP. Autoimmune PAP is rarely associated with systemic autoimmune diseases, and the present case is the first case of autoimmune PAP associated with SLE. Moreover, the present case suggests that immunosuppressive therapy should be avoided or used carefully for the treatment of patients with anti-GM-CSF antibody, such as those with autoimmune PAP.
ACCESSION #
89808984

 

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