Plasmodium vivax associated severe malaria complications among children in some malaria endemic areas of Ethiopia

Ketema, Tsige; Bacha, Ketema
August 2013
BMC Public Health;2013, Vol. 13 Issue 1, p1
Academic Journal
Background: Although, Plasmodium vivax is a rare parasite in most parts of Africa, it has significant public health importance in Ethiopia. In some parts of the country, it is responsible for majority of malaria associated morbidity. Recently severe life threatening malaria syndromes, frequently associated to P. falciparum, has been reported from P. vivax mono-infections. This prompted designing of the current study to assess prevalence of severe malaria complications related to P. vivax malaria in Ethiopia. Methods: The study was conducted in two study sites, namely Kersa and Halaba Kulito districts, located in southwest and southern parts of Ethiopia, respectively. Children, aged = 10 years, who visited the two health centers during the study period, were recruited to the study. Clinical and demographic characteristics such as age, sex, temperature, diarrhea, persistent vomiting, confusion, respiratory distress, hepatomegaly, splenomegaly, hemoglobinuria, and epitaxis were assessed for a total of 139 children diagnosed to have P. vivax mono-infection. Parasitological data were collected following standard procedures. Hemoglobin and glucose level were measured using portable hemocue instrument. Results: Median age of children was 4.25 ± 2.95 years. Geometric mean parasite count and mean hemoglobin level were 4254.89 parasite/µl and 11.55 g/dl, respectively. Higher prevalence rate of malaria and severe malaria complications were observed among children enrolled in Halaba district (P < 0.001). However, severe parasitemia was higher (72.4%) among children who visited Serbo health center (Kersa district). Male children had significantly higher risk of malaria infection (OR = 1.9, 95% CI, 1.08 to 3.34), while female had higher risk to anemia (OR = 1.91, 95% CI, 1.08 - 3.34). The observed number of anemic children was 43%, of which most of them were found in age range from 0-3 years. Furthermore, P. vivax malaria was a risk factor for incidence of anemia (P < 0.05) in the two sites. Conclusion: P. vivax associated severe malaria complications observed in this study was lower than those reported from other countries. However, incidence of severe malaria complications in one of the sites, Halaba district, where there is highest treatment failure to first line drug, could have significant impact on national malaria prevention and control activities.


Related Articles

  • The Importance of Being vivax. Bassat, Quique // Journal of Tropical Pediatrics;Oct2014, Vol. 60 Issue 5, p335 

    No abstract available.

  • Malaria vivax and Severe Thrombocytopenia in Iran. Metanat, M.; Sharifi-Mood, B. // Iranian Journal of Parasitology;2010, Vol. 5 Issue 3, p69 

    The article reports on the prevalence of malaria vivax and the severity of thrombocytopenia in Sistan and Baluchestan Province, Iran. It mentions that the occurrence of severe thrombocytopenia in Plasmodium vivax is rare though the hematological changes are nearly the same in malaria infection....

  • Plasmodium vivax Malaria during Pregnancy, Bolivia. Brutus, Laurent; Santalla, José; Schneider, Dominique; Avila, Juan Carlos; Deloron, Philippe // Emerging Infectious Diseases;Oct2013, Vol. 19 Issue 10, p1605 

    Plasmodium vivax is a major cause of illness in areas with low transmission of malaria in Latin America, Asia, and the Horn of Africa. However, pregnancy-associated malaria remains poorly characterized in such areas. Using a hospital-based survey of women giving birth and an antenatal survey, we...

  • Severe Plasmodium vivax malaria among sudanese children at New Halfa Hospital, Eastern Sudan. Mahgoub, Hyder; Gasim, Gasim I; Musa, Imad R; Adam, Ishag // Parasites & Vectors;2012, Vol. 5 Issue 1, p154 

    Background: There are few published reports on severe Plasmodium vivax malaria in Africa. Methods: Clinical pattern/manifestations of severe P. vivax were described in children admitted at New Halfa Hospital in Sudan between September 2009-December 2011. Results: Eighteen children were admitted...

  • Plasmodium vivax and Mixed Infections Are Associated with Severe Malaria in Children: A Prospective Cohort Study from Papua New Guinea. Genton, Blaise; D'Acremont, Valrie; Rare, Lawrence; Baea, Kay; Reeder, John C; Alpers, Michael P; Müller, Ivo // PLoS Medicine;Jun2008, Vol. 5 Issue 6, pe127 

    In a study carried out in Papua New Guinea, Blaise Genton and colleagues show thatPlasmodium vivax is associated with severe malaria.

  • Malaria Among the Students of Religious Schools of Bannu District, Khyber Pakhtunkhwa, Pakistan. Awan, Zia ur Rahman; Shah, Hafiz Tayyeb Ali; Shah, Abdul Haleem; Khan, Murad Ali; Suleman, Muhammad // Pakistan Journal of Zoology;2012, Vol. 44 Issue 4, p959 

    The article assesses the prevalence of malaria among the students of religious schools of Bannum District, Pakistan, using data from a parasitological survey conducted from March to May 2002. The prevalence of malaria was also explored in relation to urban and rural localities, nature of...

  • Prevalence of Human Malaria Infection in Pakistani Areas Bordering Iran: District Turbat, Pakistan. Yasinzai, Mohammad Iqbal; Kakarsulemankhel, Juma Khan // Pakistan Journal of Zoology;2012, Vol. 44 Issue 6, p1769 

    This paper reports the prevalence of malarial parasites in the human population of District Turbat. Out of a total of 5912 blood samples 46.4% were found positive for malarial parasite. The incidence of Plasmodium falciparium was 69.4% and P. vivar was 30.5%. The incidence was higher (72.1%) in...

  • Accurate identification of the six human Plasmodium spp. causing imported malaria, including Plasmodium ovale wallikeri and Plasmodium knowlesi. Calderaro, Adriana; Piccolo, Giovanna; Gorrini, Chiara; Rossi, Sabina; Montecchini, Sara; Dell'Anna, Maria Loretana; De Conto, Flora; Medici, Maria Cristina; Chezzi, Carlo; Arcangeletti, Maria Cristina // Malaria Journal;2013, Vol. 12 Issue 1, p1 

    Background: Accurate identification of Plasmodium infections in non-endemic countries is of critical importance with regard to the administration of a targeted therapy having a positive impact on patient health and management and allowing the prevention of the risk of re-introduction of endemic...

  • Çorum'da 2006-2011 Yılları Arasında Sitma Epidemlyolojisi. İnanç, Tanju; Kuk, Salih; Yazar, Süleyman // Kafkas Universitesi Veteriner Fakultesi Dergisi;2012 Supplement, Vol. 18, pA97 

    Malaria is the leading cause of morbidity and mortality among parasitic infections. About 3.3 billion people - half of the world's population - are at risk of malaria. Every year, this leads to about 250 million malaria cases and nearly one million deaths. The number of malaria cases in recent...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics