TITLE

Urinary Fluoride Excretion in 6- to 7-Year-Olds Ingesting Milk Containing 0.5 or 0.9 mg Fluoride

AUTHOR(S)
Maguire, A.; Walls, R.; Steen, N.; Teasdale, L.; Landes, D.; Omid, N.; Moynihan, P.; Zohoori, F.V.
PUB. DATE
August 2013
SOURCE
Caries Research;Aug2013, Vol. 47 Issue 4, p291
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Effectiveness of 0.5 mg fluoride (F) milk ingestion in preventing caries has been termed only 'moderate'. In this 3-arm partial cross-over intervention, 32 children aged 6-7 years in a non-F area were recruited and urinary F excretion (UFE) measured before and after ingestion of 0.5 or 0.9 mg F milk. Maintaining customary dietary and oral hygiene habits, children underwent a 2-week 'wash-in' with non-F milk, providing a 24-hour urine sample on day 4 of non-F (baseline) and F milk ingestion containing either (i) 0.5 mg or (ii) 0.9 mg F (intervention). A comparative group of thirteen 6- to 7-year-olds living in fluoridated areas provided a 24-hour urine sample on day 4 of daily non-F milk ingestion, following a 2-week non-F milk wash-in. Valid urine samples were analysed for F and UFE estimated from corrected 24-hour urine volume and F concentration. For the 24 test children providing 2 valid urine samples, mean (95% CI) change in corrected 24-hour UFE was 0.130 (0.049, 0.211) and 0.153 (0.062, 0.245) mg/day for 0.5 mg (p < 0.007) and 0.9 mg F (p < 0.001) groups, respectively. Post-intervention, mean (SD) corrected 24-hour UFE was 0.437 (0.153) mg/day and 0.420 (0.188) mg/day for the 0.5 and 0.9 mg F groups, respectively, which were lower than the WHO provisional standards (0.48-0.60 mg F/day). F milk consumption significantly increased UFE; however, the F content of 0.5 and 0.9 mg F milk may be too low to achieve WHO provisional UFE standards concomitant with optimal F exposure in children aged ≥6 years. Copyright © 2013 S. Karger AG, Basel
ACCESSION #
89595870

 

Related Articles

  • Caries-Preventive Effect of Salt Fluoridation in Preschool Children in The Gambia: A Prospective, Controlled, Interventional Study. Jordan, Rainer A.; Schulte, Andreas; Bockelbrink, Alexander C.; Puetz, Sarah; Naumova, Ella; Wärn, Lars G.; Zimmer, Stefan; Wärn, Lars G // Caries Research;Jan2018, Vol. 51 Issue 6, p596 

    The aim of this study was to investigate the anticaries effect of fluoridated salt in a communal feeding program for preschool children. In the Gambian city of Brikama, drinking water had a low fluoride content (0.1 mg F-/L) and young children did not use toothpaste for oral hygiene. Its 2...

  • Effect of School-Based Fluoride Varnish Programmes on Approximal Caries in Adolescents from Different Caries Risk Areas. U. Moberg Sköld; L.G. Petersson; A. Lith; D. Birkhed // Caries Research;Jul/Aug2005, Vol. 39 Issue 4, p273 

    The aim was to evaluate, in a 3-year RCT study, school-based fluoride varnish programme on approximal caries incidence and approximal caries progression in 13- to 16-year-olds in high, medium and low caries risk areas on the Swedish west coast. Seven hundred and fifty-eight (89%) fulfilled the...

  • Mutans Streptococci and Caries Prevalence in Children after Early Maternal Caries Prevention: A Follow-Up at 19 Years of Age. Köhler, B.; Andréen, I. // Caries Research;2012, Vol. 46 Issue 5, p474 

    Aim: The efficacy of early maternal caries prevention was evaluated. Furthermore, the difference between children colonised with mutans streptococci (MS) at an early or late stage with regard to the prevalence of carious lesions was determined. Methods: The children of first-time mothers...

  • Mutual Medical Dental Problems: Fluoridation of Water Supply. NAHUM, LOUIS H. // Connecticut Medicine;Mar2015, Vol. 79 Issue 3, p177 

    A reprint of the article "Mutual Medical Dental Problems: Fluoridation of Water Supply," by Louis H. Nahum, which appeared in the 1965 issue of "Connecticut Medicine". It discusses the role of fluoridation of water supply in the reduction of dental carries in the U.S., the mechanism by which...

  • Risk Groups: Nursing Bottle Caries/Caries in the Elderly. Curzon, M. E. J.; Preston, A. J. // Caries Research;Jan/Feb2004 Supplement 1, Vol. 38, p24 

    Provides information on the prevention of dental caries both in children and the elderly. Diet and dental cries in the very young and elderly; Etiology and factors of nursing caries; Prevalence of nursing caries in pre-school children; Etiology and prevalence of root caries among the elderly.

  • Low-Fluoride Dentifrice and Caries Lesion Control in Children with Different Caries Experience: A Randomized Clinical Trial. Lima, T. J.; Ribeiro, C. C. C.; Tenuta, L. M. A.; Cury, J. A. // Caries Research;2008, Vol. 42 Issue 1, p46 

    Since there is no consensus on the anticaries effectiveness of low-fluoride (F) dentifrice, this randomized clinical trial evaluated its effect in children at different caries activity status. One hundred and twenty 2- to 4-year-old children, half with and half without active caries lesions,...

  • Effects of Programs for Prevention of Early Childhood Caries. Ammari, Jumana B.; Baqain, Zaid H.; Ashley, Paul F. // Medical Principles & Practice;Nov2007, Vol. 16 Issue 6, p437 

    Objective: To determine the most effective intervention program for prevention of early childhood caries. Materials and Methods: All studies published after 1966 were identified by searching electronic databases (Medline, The Cochrane Library, Embase, Dissertation and Serfile databases) and...

  • CARIES PREVENTION--FLUORIDE. CLARKSON, B. H. // Advances in Dental Research;Dec1991, Vol. 5 Issue 1, p41 

    A clear understanding of the mechanism of action of fluoride and its pharmacokinetics would ensure appropriate clinical use of fluoride and fluoride-containing modalities. Convincing evidence exists that fluoride has a major effect on the demineralization and remineralization of dental hard...

  • CARIES PREVENTION--FLUORIDE: REACTION PAPER. BOWEN, W. H. // Advances in Dental Research;Dec1991, Vol. 5 Issue 1, p46 

    Although the prevalence of caries has declined in young persons in developed countries, there is still a need for water fluoridation. The effectiveness of fluoride is dependent on the ambient levels of fluoride in the oral cavity. Fluoride appears to exert the bulk of its protective effect...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics