Pakshir, Keyvan
July 2013
Jundishapur Journal of Microbiology;2013 Special Edition, p3
Academic Journal
The fungi secrets specific enzymes to destroy materials as a part of their life style that play a critical role in their pathogenesis. Invasion by the fungi has been occurred by a combination of mechanical pressure and enzymatic hydrolysis which are important factors for virulence. Some fungi produce proteases and lipases which help them invade the tissues. Candida albicans produces asparatic proteases; lipases and phospholipase which play an important role in their virulence. There are many other exoenzymes such as hemolysin, coagulase, esterase and keratinase that help the fungi for infection. Some of these enzymes are measurable and con be identified by several methods. For example, phospholipase, esterase and hemolytic activity in Candida species con be detected by egg yolk agar, Tween 80 opacity test and blood plate assay, respectively. Fungal exoenzymes give a useful data about fungal pathogenesis and their virulence.


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