TITLE

Quando utilizar terapia empírica em doenças fúngicas invasivas?

AUTHOR(S)
Nucci, Marcio; Colombo, Arnaldo Lopes
PUB. DATE
April 2012
SOURCE
Revista Panamericana de Infectologia;2012, Vol. 14 Issue 1, p32
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Empirical therapy refers to a practice of starting antimicrobial therapy before the diagnosis of infection is established. Empirical antifungal therapy is justified by the high incidence, difficult diagnosis and poor prognosis of invasive fungal diseases in high-risk patients. This strategy is well-established as standard of care in persistently febrile neutropenic cancer patients, although efforts have been made to change the non-specific fever as trigger for starting antifungal therapy to a diagnostic-driven approach. Outside the scenario of febrile neutropenia, empirical antifungal therapy has been used in managing critically ill patients with sepsis of unknown etiology, although the strategy and the criteria for selecting high-risk patients have not been established.
ACCESSION #
89531016

 

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