TITLE

Comparator bias: why comparisons must address genuine uncertainties

AUTHOR(S)
Mann, Howard; Djulbegovic, Benjamin
PUB. DATE
January 2013
SOURCE
JRSM Cardiovascular Disease;Jan2013, Vol. 106 Issue 1, p30
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article discusses the problem of comparator bias in controlled clinical trials. It is noted that comparator bias is introduced when treatments known to be beneficial are withheld from patients participating in controlled trials. The article also discusses the inappropriate use of inactive comparators and several ways to reduce comparator bias.
ACCESSION #
89524447

 

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