TITLE

Detection Of Hepatitis B Surface Antigen (HBsAg) Among Children In Ibadan, Southwestern Nigeria

AUTHOR(S)

Okonko, I.O.; Okerentugba, P.O.; Innocient-Adiele, H.C.

PUB. DATE

January 2012

SOURCE

Internet Journal of Infectious Diseases;2012, Vol. 10 Issue 1, p1

SOURCE TYPE

Academic Journal

DOC. TYPE

Article

ABSTRACT

This study was carried out to detect hepatitis B surface antigen (HBsAg) and risk factors of transmission among children in Ibadan, Oyo State, Southwestern Nigeria. In order to estimate the prevalence rate of HBsAg and to evaluate the influence of children demographics on HBsAg seropositivity, well-designed questionnaire was used to obtain data considered risk factors for contracting HBsAg from consenting children. A total of 217 blood samples were collected from children attending the Oni Memorial Children Hospital, Ibadan. The male:female ratio was 1:1. One hundred and nine of the children were females [109(50.2%)] while males were [108(49.8%). Blood samples were screened by parallel diagnostic method using Dia Spot HBsAg test kit and One Step Strip Style HBsAg test kit (Global Diagnostic Canada) for HBsAg. Overall prevalence rate of HBsAg was 0.5%. It showed that HBsAg prevalence was higher among age group >1-12 years, a total of 184 samples were tested, of which one (1) tested positive for HBsAg, thus, giving the prevalence of 0.5%. All other age groups showed zero seroposivity. There was significant association (P>0.05) between age groups and HBsAg infection acquisition. HBsAg was only found among male children [1(0.9%)]. There was significant association (P>0.05) between sex and HBsAg infection acquisition among these population. HBsAg was higher among children with history of vaccinations [1(0.6%)] than their counterparts without history of vaccinations [0(0.0%)]. There was significant association (P>0.05) between history of vaccination and HBsAg infection acquisition among these population. This study however confirmed the presence of HBsAg among children in Oyo State, Nigeria. General surveillance, mass immunization and public health education to stop the spread of the infection on among children in Ibadan and indeed the whole society is advocated.

ACCESSION #

89330504

 

Related Articles

• Knowledge Level of Hepatitis B and its Prevalance in Policemen Working in Adiyaman. Kölgelier, Servet; Demir, Nazlım Aktuğ; Demir, Lütfi Saltuk; Özçimen, Serap; İnkaya, Ahmet Çağkan // European Journal of General Medicine;2015, p114 

  Aim of this study to investigate the level of knowledge about hepatitis B and prevalence of HBsAg carriage in police and other security staff. Hepatitis B knowledge of police and other staff working for Adiyaman police department were measured using a questionnaire. This questionnaire was...

• Child drowning deaths in Aydin province, western Turkey, 2002-2012. Dirlik, M.; Bostancıoğlu, B. // European Journal of Trauma & Emergency Surgery;Dec2015, Vol. 41 Issue 6, p683 

  Introduction: Drowning, a major public health problem worldwide, occurs as an accident, suicide, or homicide. Deaths with an accidental origin are common in childhood in the 0-18 age group. In our study, pediatric drowning cases for whom a postmortem examination and an autopsy were conducted by...

• Intensity of HLA-A2 Expression Significantly Decreased in Occult Hepatitis B Infection. Askari, Azam; Hassanshahi, Gholam Hossein; Ghalebi, Seyed Razi; Jafarzadeh, Abdollah; Mohit, Maryam; Hajghani, Masomeh; Arababadi, Mohammad Kazemi // Jundishapur Journal of Microbiology;Jun2014, Vol. 7 Issue 6, p1 

  Background: Occult hepatitis B infected (OBI) patients cannot eradicate hepatitis B virus (HBV)-DNA from their liver and peripheral blood, completely. Objectives: The main aim of this study was to investigate the rate of HLA-A2 expression on peripheral blood mononuclear cells (PBMCs) of patients...

• Using Survey Results Regarding Hepatitis B Knowledge, Community Awareness and Testing Behavior Among Asians to Improve the San Francisco Hep B Free Campaign. Shiau, Rita; Bove, Fred; Henne, Jeff; Zola, Janet; Fang, Ted; Fernyak, Susan // Journal of Community Health;Apr2012, Vol. 37 Issue 2, p350 

  Asians are disproportionately affected by chronic hepatitis B (HBV) infection and its fatal consequences. The Hep B Free campaign was launched to eliminate HBV in San Francisco by increasing awareness, testing, vaccination and linkage to care. The campaign conducted 306 street intercept and...

• Hepatitis B virus part 1: risk factors, blood results and nursing care. Jack, Kate; Cooper, Joanne; Ryder, Stephen // Gastrointestinal Nursing;Apr2013, Vol. 11 Issue 3, p37 

  Chronic hepatitis B virus (HBV) is the most prevalent of the world's blood-borne viral infections. It may lead to liver cirrhosis, end-stage liver disease or hepatocellular carcinoma. HBV is spread via percutaneous and permucosal exposure to infected body fluids. The small numbers of people in...

• Polymorphisms within the Promoter Region of the Gamma Interferon (IFN-γ) Receptor1 Gene are Associated with the Susceptibility to Chronic HBV Infection in an Iranian Population. Khanizadeh, Sayyad; Ravanshad, Mehrdad; Mohebbi, Seyed Reza; Naghoosi, Hamed; Tahaei, Mohamad Abrahim; Nasab, Seyed Dawood Mousavi; Romani, Sara; Azimzadeh, Pedram; Sanati, Azar; Zali, Mohammad Reza // Hepatitis Monthly;2012, Vol. 12 Issue 11, p1 

  Background: chronic hepatitis B virus (HBV) infection is a multifactorial disease that can result in serious clinical complications. Host genetic background especially the genes that encode immunologic factors like INF-γ and its receptor (IFN-γ R) are critical in the pathogenesis of...

• Letter from the Editor.  // Eastern Mediterranean Health Journal;jan/feb2009, Vol. 15 Issue 1, p4 

  The article discusses various reports on cancer published within the issue, including one on mammography screening for breast cancer in Lebanon, another on the prevalence of mesothelioma due to occupational and environmental exposure to asbestos in Egypt, and a report on the prevalence of...

• Seroprevalence and risk factors for hepatitis B and C virus infection in Damietta Governorate, Egypt. Edris, A.; Nour, M.O.; Zedan, O.O.; Mansour, A.E.; Ghandour, A.A.; Omran, T. // Eastern Mediterranean Health Journal;Oct2014, Vol. 20 Issue 10, p605 

  Hepatitis B and C virus (HBV and HCV) infections remain major public health problems in Egypt and data are needed on risk factors for infection. This study determined the prevalence of anti-HCV and HBV surface antigen seropositivity in Damietta Governorate, Egypt, and evaluated potential risk...

• Prevalence of hepatitis D virus in hepatitis B virus infected patients referred to Taleghani hospital, Tehran, Iran. Tahaei, Seyed Mohammad Ebrahim; Mohebbi, Seyed Reza; Azimzadeh, Pedram; Behelgardi, Abbas; Sanati, Azar; Mohammadi, Parvaneh; Khanyaghma, Mahsa; Razavi, Armin Hosseini; Sharifian, Afsaneh; Zali, Mohammad Reza // Gastroenterology & Hepatology from Bed to Bench;Summer2014, Vol. 7 Issue 3, p144 

  Aim: The aim of this study was to determine the prevalence of HDV infection between HBV chronic patients referred to gastroenterology ward of Taleghani hospital Tehran, Iran and also investigating the risk factors in acquiring the HDV infection. Background: Hepatitis B virus (HBV) and Hepatitis...

Read the Article