Detection Of Hepatitis B Surface Antigen (HBsAg) Among Children In Ibadan, Southwestern Nigeria

Okonko, I.O.; Okerentugba, P.O.; Innocient-Adiele, H.C.
January 2012
Internet Journal of Infectious Diseases;2012, Vol. 10 Issue 1, p1
Academic Journal
This study was carried out to detect hepatitis B surface antigen (HBsAg) and risk factors of transmission among children in Ibadan, Oyo State, Southwestern Nigeria. In order to estimate the prevalence rate of HBsAg and to evaluate the influence of children demographics on HBsAg seropositivity, well-designed questionnaire was used to obtain data considered risk factors for contracting HBsAg from consenting children. A total of 217 blood samples were collected from children attending the Oni Memorial Children Hospital, Ibadan. The male:female ratio was 1:1. One hundred and nine of the children were females [109(50.2%)] while males were [108(49.8%). Blood samples were screened by parallel diagnostic method using Dia Spot HBsAg test kit and One Step Strip Style HBsAg test kit (Global Diagnostic Canada) for HBsAg. Overall prevalence rate of HBsAg was 0.5%. It showed that HBsAg prevalence was higher among age group >1-12 years, a total of 184 samples were tested, of which one (1) tested positive for HBsAg, thus, giving the prevalence of 0.5%. All other age groups showed zero seroposivity. There was significant association (P>0.05) between age groups and HBsAg infection acquisition. HBsAg was only found among male children [1(0.9%)]. There was significant association (P>0.05) between sex and HBsAg infection acquisition among these population. HBsAg was higher among children with history of vaccinations [1(0.6%)] than their counterparts without history of vaccinations [0(0.0%)]. There was significant association (P>0.05) between history of vaccination and HBsAg infection acquisition among these population. This study however confirmed the presence of HBsAg among children in Oyo State, Nigeria. General surveillance, mass immunization and public health education to stop the spread of the infection on among children in Ibadan and indeed the whole society is advocated.


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