Are Major Basic Protein, Eotaxin-3 and Leukotriene Enzyme Staining Useful for Diagnosing Eosinophilic Esophagitis?

Kim, Jie-Hyun
January 2013
Journal of Neurogastroenterology & Motility;Jan2013, Vol. 19 Issue 1, p112
Academic Journal
The article focuses on a clinical study conducted to find the factors for diagnosis of eosinophilic esophagitis (EoE) to differentiate it from gastroesophageal reflux disease (GERD) and discusses the comment on study. The study found more amount of major basic protein (MBP) and eotaxin-3 are present in EoE patients as compared to GERd so they can be used as biomarker to diagnos EoE. It states that EoE the diagnostic markers may be used for differentiating it from GERD rather then in diagnosis.


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