Metabolic disorders: Betatrophin boosts β-cells

Crunkhorn, Sarah
July 2013
Nature Reviews Drug Discovery;Jul2013, Vol. 12 Issue 7, p504
Academic Journal
The article discusses research being done on a novel liver-secreted hormone called betatrophin. It references a study by P. Yi et al published in a 2013 issue of "Cell."According to the study, an adult mice infused with a 43-amino-acid peptide showed glucose intolerance, insulin resistance, β-cell proliferation and β-cell mass expansion. The study also found that betatrophin led to a rise in the rate of β-cell proliferation.


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