Cancer: IL-22: linking inflammation and cancer

Harrison, Charlotte
July 2013
Nature Reviews Drug Discovery;Jul2013, Vol. 12 Issue 7, p504
Academic Journal
The article discusses research being done on the role of interleukin-22 (IL-22) in the transition from intestinal inflammation to cancer. It references a study by S. Kirchberger et al published in a 2013 issue of the "Journal of Experimental Medicine." Mice served as subjects in this study. Results of the study showed that there is increased innate lymphoid cells and messenger RNA levels in mice with colon cancer. It notes that both IL-17 and IL-22 are produced by the innate lymphoid cells.


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