Prospective study of the progression of low-grade dysplasia in ulcerative colitis using current cancer surveillance guidelines

Brentnall, T. A.
January 2013
Inflammatory Bowel Disease Monitor;2013, Vol. 13 Issue 3, p116
Academic Journal
A review of the article "Prospective study of the progression of low-grade dysplasia in ulcerative colitis using current cancer surveillance guidelines," by T. L. Zisman and colleagues, which appeared in the periodical "Digestive Diseases and Sciences" on January 11, 2013 is presented.


Related Articles

  • The fate of low grade dysplasia in ulcerative colitis Ullman, Thomas A.; Loftus Jr, Edward V.; Kakar, Sanjay; Burgart, Lawrence J.; Sandborn, William J.; Tremaine, William J. // American Journal of Gastroenterology;Apr2002, Vol. 97 Issue 4, p922 

    OBJECTIVE:The optimal strategy for the management of definite low grade dysplasia (LGD) detected in surveillance in ulcerative colitis (UC) is unknown, because the natural history of LGD has not been well described.METHODS:We reviewed the Mayo Clinic records of patients with UC found to have...

  • DYSPLASIA IN ULCERATIVE COLITIS IS USUALLY VISIBLE AT COLONOSCOPY. Rutter, M.D.; Wilkinson, K.H.; Saunders, B.P. // Gut;Apr2003 Supplement 1, Vol. 52, pA4 

    Background and Aim: During colonoscopic surveillance for dysplasia in longstanding extensive ulcerative colitis (UC), multiple non-targeted "random" biopsies of colonic mucosa are advised, based on historical data suggesting dysplasia may only be detectable microscopically. We aimed to assess...

  • Telomere shortening in the colonic mucosa of patients with ulcerative colitis. Kinouchi, Yoshitaka; Hiwatashi, Nobuo; Chida, Masaki; Nagashima, Fumio; Takagi, Sho; Maekawa, Hiroki; Toyota, Takayoshi; Kinouchi, Y; Hiwatashi, N; Chida, M; Nagashima, F; Takagi, S; Maekawa, H; Toyota, T // Journal of Gastroenterology;1998, Vol. 33 Issue 3, p343 

    Telomere length in human somatic cells gradually decreases with the number of cell divisions and is regarded as a marker of somatic cell turnover. Mucosal cells of the affected colon show rapid turnover in individuals with active ulcerative colitis (UC). Telomere length was determined by...

  • THE RISK OF DYSPLASIA IN POST-SURGICAL COLORECTAL MUCOSA IN ULCERATIVE COLITIS. Rutter, M.D.; Saunders, B.P. // Gut;Apr2003 Supplement 1, Vol. 52, pA95 

    Background and Aim: Although panproctocolectomy (PPC) is the operation of choice in longstanding extensive ulcerative colitis (UC), other procedures are occasionally chosen, leaving the patient at risk of dysplasia/cancer in the colorectal remnant. We aimed to assess this risk. Methods:...

  • Modelling dysplasia detection in ulcerative colitis: clinical implications of surveillance intensity. D Awais // Gut;Nov2009, Vol. 58 Issue 11, p1498 

    BACKGROUND: Endoscopic surveillance of chronic colitis uses random biopsies to find dysplastic fields. Enhanced endoscopic methods are more sensitive for dysplasia detection, but their specificity for colorectal cancer risk is unknown. AIMS: To develop a mathematical model of the sensitivity of...

  • The Risk of Cancer and Dysplasia among Ulcerative Colitis Patients with Primary Sclerosing Cholangitis. Marchesa, Pierenrico; Lashner, Bret A.; Lavery, Ian C.; Milsom, Jeffrey; Hull, Tracy L.; Strong, Scott A.; Church, James M.; Navarro, Georgia; Fazio, Victor W. // American Journal of Gastroenterology;Aug1997, Vol. 92 Issue 8, p1285 

    Background: Ulcerative colitis (UC) patients with primary sclerosing cholangitis (PSC) may have an increased risk for colonic dysplasia or cancer. They also may have higher levels of carcinogenic secondary bile acids and, thus, be more likely to develop cancer in the right side of the colon,...

  • Conservative Management of Small Adenomata in Ulcerative Colitis. Medlicott, S. A. C.; Jewell, L. D.; Price, L.; Fedorak, R. N.; Sherbaniuk, R. W.; Urbanski, S. J. // American Journal of Gastroenterology;Nov1997, Vol. 92 Issue 11, p2094 

    Objective and Methods: Patients with chronic ulcerative colitis may develop colitis-related dysplasia and/or sporadic adenomata. Differentiating between these two processes is important because they may dictate different therapeutic approaches. Although distinguishing features of sporadic...

  • Physicians' Perceptions of Dysplasia and Approaches to Surveillance Colonoscopy in Ulcerative Colitis. Bernstein, Charles N.; Weinstein, Wilfred M.; Levine, Douglas S.; Shanahan, Fergus // American Journal of Gastroenterology;Dec1995, Vol. 90 Issue 12, p2106 

    Objective: Colonoscopic biopsy surveillance to detect dysplasia, defined as a neoplastic change of the epithelium without invasion into the lamina propria, in patients with ulcerative colitis has become a widespread practice. We undertook a survey study to determine physicians' perceptions of,...

  • Delayed Perforation of the Cecum after Diagnostic Biopsy. Loggan, Michael; Moeller, Donald D. // American Journal of Gastroenterology;Dec1984, Vol. 79 Issue 12, p933 

    Colonoscopy is an important diagnostic study in monitoring patients with chronic ulcerative colitis for carcinoma and dysplasia (precancer). A 76-year-old woman with chronic ulcerative colitis of 13 years' duration underwent colonoscopy. Biopsies were obtained at 10-cm intervals throughout the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics