Axon guidance mechanisms: semaphorins as simultaneous repellents and anti-repellents
Tags: NEUROPILINS; MEMBRANE proteins; AXONS
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Neuropilin-1 (NP-1) has been identified as a necessary component of a semaphorin D (SemD) receptor that repulses dorsal root ganglion (DRG) axons during development. SemA and SemE are related to SemD and bind to NP-1, but do not repulse DRG axons. By expressing NP-1 in retinal neurons and NP-2...
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An encyclopedia entry for "axon" is presented. It refers to a specialized, elongated neuronal process engaged in sending information over relatively long distances. It notes that the axonal membrane has embedded protein molecules that are used as ionic channels and enzymes. Axons may also be...
