Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance

Hirakawa, Hidetada; Tomita, Haruyoshi
May 2013
Frontiers in Microbiology;May2013, Vol. 4, p1
Academic Journal
No abstract available.


Related Articles

  • Targeting the bacteria-host interface. Krachler, Anne Marie; Orth, Kim // Virulence;May2013, Vol. 4 Issue 4, p284 

    Bacterial infections are a major cause of morbidity and mortality worldwide and are increasingly problematic to treat due to the rise in antibiotic-resistant strains. it becomes more and more challenging to develop new antimicrobials that are able to withstand the ever-increasing repertoire of...

  • Anti-virulence strategies to combat bacteria-mediated disease. Rasko, David A.; Sperandio, Vanessa // Nature Reviews Drug Discovery;Feb2010, Vol. 9 Issue 2, p117 

    Antibiotic resistance is one of the greatest challenges of the twenty-first century. However, the increasing understanding of bacterial pathogenesis and intercellular communication has revealed many potential strategies to develop novel drugs to treat bacteria-mediated disease. Interference with...

  • UTI antimicrobial resistance patterns vary worldwide. Prescott, Lawrence M. // Urology Times;Apr2002, Vol. 30 Issue 4, p1 

    Reports on the variation of antimicrobial resistance patterns against urinary tract infections worldwide. Presentation of the reports at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy; Effectiveness of ciprofloxacin against any species of bacterial isolates;...

  • Implications of endophyte-plant crosstalk in light of quorum responses for plant biotechnology. Kusari, Parijat; Kusari, Souvik; Spiteller, Michael; Kayser, Oliver // Applied Microbiology & Biotechnology;Jul2015, Vol. 99 Issue 13, p5383 

    Quorum sensing, the cell-to-cell communication system mediated by autoinducers, is responsible for regulation of virulence factors, infections, invasion, colonization, biofilm formation, and antibiotic resistance within bacterial populations. Concomitantly, quorum quenching is a process that...

  • Bacteriophage: Time to Re-Evaluate the Potential of Phage Therapy as a Promising Agent to Control Multidrug-Resistant Bacteria. Ghannad, Masoud Sabouri; Mohammadi, Avid // Iranian Journal of Basic Medical Sciences;Mar/Apr2012, Vol. 15 Issue 2, p693 

    Nowadays the most difficult problem in treatment of bacterial infections is the appearance of resistant bacteria to the antimicrobial agents so that the attention is being drawn to other potential targets. In view of the positive findings of phage therapy, many advantages have been mentioned...

  • New approaches to the control of infections caused by antibiotic-resistant bacteria. Chopra, Ian; Hodgson, John // JAMA: Journal of the American Medical Association;2/7/96, Vol. 275 Issue 5, p401 

    Opinion. Studies new approaches to treating infections caused by drug-resistant bacterial strains. Emergence of antibiotic-resistant bacteria and consequences; Circumventing resistance to established antibiotics; Decreased dependence on established antibiotics; Search for new antimicrobials.

  • "Compounding Irresponsibility: The Unpalatable Triad of Bad Science, Bad Refereeing, and Bad Journalism.". Kurtz, K. S. // Journal of Dental Research;Jun1994, Vol. 73 Issue 6, p1130 

    The author criticizes the "New York Times" newspaper for publishing a story he believes to be based on faulty scientific research, titled "New Suspect in Bacterial Resistance: Amalgam," subtitled "The Mercury in Dental Fillings May Spur Resistance to Antibiotics," on April 27, 1993. The "New...

  • Antimicrobial and Antiparasitic Activity of Lectins. Iordache, Florin; Ionita, Mariana; Mitrea, Liviu Ioan; Fafaneata, Cornelia; Pop, Aneta // Current Pharmaceutical Biotechnology;Feb2015, Vol. 16 Issue 2, p152 

    Antibiotic resistance is a major problem in current contemporary medicine and it has become a major concern of the 21st century. New resistance mechanisms developed by microorganisms spread greatly, threatening the ability to treat numerous infectious diseases, and increasing the number of...

  • Antisense RNA regulation and application in the development of novel antibiotics to combat multidrug resistant bacteria. Ji, Yinduo; Lei, Ting // Science Progress;Mar2013, Vol. 96 Issue 1, p43 

    Despite the availability of antibiotics and vaccines, infectious diseases remain one of most dangerous threats to humans and animals. The overuse and misuse of antibacterial agents have led to the emergence of multidrug resistant bacterial pathogens. Bacterial cells are often resilient enough to...

  • Review: Inhibition of bacterial quorum sensing by plant extracts. Yarmolinsky, Ludmila; Bronstein, Moshe; Gorelick, Jonathan // Israel Journal of Plant Sciences;Nov2015, Vol. 62 Issue 4, p294 

    Bacterial quorum sensing (QS) is a form of cell-to-cell communication which is vital to the pathogenicity of many bacteria, and therefore a promising target for the development of new treatments for microbial infections. While many medicinal plants possess antibacterial activity, only a few...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics