TITLE

Correction of impairments in functions of anticoagulation and insular systems of an organism by the regulatory peptide Leu-Pro-Gly-Pro

AUTHOR(S)
Myasoedov, N.; Andreeva, L.; Lyapina, L.; Shubina, T.; Grigor'eva, M.; Obergan, T.
PUB. DATE
May 2013
SOURCE
Biology Bulletin;May2013, Vol. 40 Issue 3, p304
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
It has been established that fivefold intranasal administration of the peptide Leu-Pro-Gly-Pro (1 mg/kg) to rats with developing refractory hyperglycemia leads to restoration and normalization of the functions of anticoagulation and insular systems. In the blood of experimental animals, there was a decrease in the sugar level and platelet aggregation and an increase in anticoagulant and all kinds of fibrinolytic (total, enzymatic, non-enzymatic, Hageman-dependent) activity.
ACCESSION #
88059972

 

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