Mapping the Pattern and Trends of Extrapulmonary Tuberculosis

Prakasha, S. Rama; Suresh, G.; D'sa, Ivor Peter; Shetty, Shobha S.; Kumar, S. Ganesh
April 2013
Journal of Global Infectious Diseases;Apr-Jun2013, Vol. 5 Issue 2, p54
Academic Journal
Background and Objectives: There has been a rapid expansion of the directly observed treatment short-term (DOTS) under the revised national tuberculosis control program throughout India in the last decade. Few reports exist detailing individual DOTS centers' experiences with regard to extrapulmonary tuberculosis (EPTB) in a medical college hospital setting. Materials and Methods: This is a retrospective, record-based study of patients with the diagnosis of EPTB, in all age groups. Data on all consecutive EPTB cases diagnosed at the K. S. Hegde Medical College and Hospital, Deralakatte, Mangalore from 1 January 2005 to 31 December 2011 at the DOTS centre attached to this hospital were collected, analyzed by Mantel-Haenszel Chi square for linear trend and described in proportion or percentages. Results: Among 1267 cases registered for treatment of all forms of tuberculosis, 528 (41.67%) had EPTB. Around half of the cases of EPTB (269, 51%) were among adult age groups and the majority of cases (342, 64.77%) received Category-I treatment. Pleural TB was the commonest type of EPTB (n = 148, 28.03%), followed by lymph node TB (n = 131, 24.81%). Involvement of lymph nodes was the commonest manifestation among the less than 14 years' age group (27, 58.7%), while involvement of pleura was more common among > 65 years' age group (23, 45.1%). The difference in the occurrence of EPTB by site between males and females is statistically significant with a P value of <0.005. There is a significant increase in the number of cases of tuberculosis affecting bones and joints, and other forms of tuberculosis over the years. Conclusion: The burden of EPTB is more among the productive age group. Increase in the trend of bone and joint tuberculosis, and other rare forms of EPTB is a point of concern highlighting the importance of strengthening the services towards this group.


Related Articles

  • New tuberculosis research movement needed.  // Biomedical Market Newsletter;11/30/2011, Vol. 21, p154 

    The article presents information on the launch of the tuberculosis (TB) Research Movement by the Stop TB Partnership and the World Health Organization (WHO) Stop TB Department. It informs that the program has two key components, the analysis of the global funding landscape for TB research and...

  • WHO warns of consequences of underfunding TB.  // Africa Health;Nov2011, Vol. 34 Issue 1, p12 

    The article discusses the report of the World Health Organization (WHO) that mortality due to tuberculosis (TB) has decreased but may increase again if funding for TB programs will not be sustained.

  • TB death rate halved -- everywhere but Africa. Bateman, Chris // CME: Continuing Medical Education;Oct2011, Vol. 29 Issue 10, p433 

    The article reports that tuberculosis (TB) death rate declined in all countries except African nations, based on the World Health Organization report, where it called for additional 7.8 billion rand to finance TB treatment initiatives in 2012.

  • Plan to stop child TB deaths.  // Bulletin of the World Health Organization;Nov2013, Vol. 91 Issue 11, p803 

    The article reports on an initiative called "The Roadmap for Childhood Tuberculosis: Towards Zero Deaths" which was launched in October of 2013 by the World Health Organization and its partners to prevent pediatric tuberculosis deaths across the globe.

  • A new ambassador for TB and HIV.  // Bulletin of the World Health Organization;Jul2011, Vol. 89 Issue 7, p472 

    The article reports that Chinese singer Peng Llyuan has been appointed in 2011 as Goodwill Ambassador for Tuberculosis and HIV/AIDS of the World Health Organization to raise awareness about the diseases.

  • WHO's role in tuberculosis research. O'Brien, Richard J. // World Health;Jul/Aug93, Vol. 46 Issue 4, p13 

    Presents the role of the World Health Organization in tuberculosis research. Chosen areas of research; Area with critical need for development studies; Cooperation with WHO's Global Programme on acquired immunodeficiency syndrome; Assessing polymerase chain reaction for diagnosis.

  • Tuberculosis Notifications and Mortality in Greece During 2003 to 2012. Michas, George; Asimakos, Andreas // Hospital Chronicles;2015, Vol. 10 Issue 4, p1 

    A letter to the editor is presented which refers to the World Health Organization's report on cases of tuberculosis (TB) during financial crisis in Greece, and talks of mortality due to communicable disease, paucity of health care budget for TB surveillance, and under reporting of TB cases.

  • A world of cities and the end of TB. Prasad, Amit; Ross, Alex; Rosenberg, Paul; Dye, Christopher // Transactions of the Royal Society of Tropical Medicine & Hygiene;Mar2016, Vol. 110 Issue 3, p151 

    The WHO's End TB Strategy aims to reduce TB deaths by 95% and incidence by 90% between 2015 and 2035. As the world rapidly urbanizes, more people could have access to better infrastructure and services to help combat poverty and infectious diseases, including TB. And yet large numbers of people...

  • Detection of lipoarabinomannan (LAM) in urine is indicative of disseminated TB with renal involvement in patients living with HIV and advanced immunodeficiency: evidence and implications. Lawn, Stephen D.; Gupta-Wright, Ankur // Transactions of the Royal Society of Tropical Medicine & Hygiene;Mar2016, Vol. 110 Issue 3, p180 

    TB is the leading cause of HIV/AIDS-related deaths globally. New diagnostic tools are urgently needed to avert deaths from undiagnosed HIV-associated TB. Although simple assays that detect lipoarabinomannan (LAM) in urine have been commercially available for years, their specific role and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics