Survival following spinal cord infarction

New, P W; McFarlane, C L
June 2013
Spinal Cord;Jun2013, Vol. 51 Issue 6, p453
Academic Journal
Study design:Retrospective open cohort.Objectives:To calculate the survival of patients with spinal cord infarction and to compare the cause of death in patients with different mechanisms of ischaemic injury.Setting:Spinal Rehabilitation Unit, Melbourne, Victoria, Australia.Methods:Consecutive admissions between 1 January 1995 and 31 December 2008 with recent onset of spinal cord infarction. Linkage to the Registry of Births, Deaths and Marriages (Victoria) was used to determine survival following discharge from in-patient rehabilitation and cause of death.Results:A total of 44 patients were admitted (males=26, 59%), with a median age of 72 years (interquartile range (IQR) 62-79). One patient died during their in-patient rehabilitation programme. In all, 14 patients (n=14/44; 33%) died during the follow-up period. The median survival after diagnosis was 56 months (IQR 28-85) and after discharge from in-patient rehabilitation was 46 months (IQR 25-74). The 1- and 5-year mortality rates were 7.0% (n=3/43; 95% confidence interval (CI)=2.4-18.6%) and 20.9% (n=9/43; 95% CI=11.4-35.2%). There was no statistically significant difference in survival between patients with the different aetiologies of spinal cord infarction (other vs idiopathic: χ2=0.6, P=0.7; other vs vascular: χ2=1.9, P=0.3). There was no relationship between survival and gender (χ2=0.2, P=0.6), age (χ2=3.0, P=0.08), level of injury (χ2=0.0, P=1) or American Spinal Cord Society Impairment Scale grade of spinal cord injury (χ2=0.02, P=0.9).Conclusion:Patients with spinal cord infarction appear to have a fair survival after discharge from in-patient rehabilitation, not withstanding the occurrence of risk factors of vascular disease in many patients.


Related Articles

  • Trends in Kaposi's Sarcoma in Miami Beach from 1987 to 2007. Zeichner, Simon B.; Ruiz, Ana L.; Suciu, Gabriel P.; Zeichner, Rachel Lerner; Rodriguez, Estelamari // ISRN Oncology;2012, p1 

    Purpose. Kaposi's sarcoma (KS) is a rare low-grade vascular tumor associated with the human herpes virus 8. By analyzing the epidemiology, staging, and treatment of KS, we hoped to improve the quality of care at our institution. Methods. Review of the Mount Sinai Medical Center tumor registry...

  • Adjuvant Intravesical Bacillus Calmette-Guérin Therapy and Survival Among Elderly Patients With Non-Muscle-Invasive Bladder Cancer. Spencer, Benjamin A.; Mcbride, Russell B.; Hershman, Dawn L.; Buono, Donna; Herr, Harry W.; Benson, Mitchell C.; Gupta-Mohile, Supriya; Neugut, Alfred I. // Journal of Oncology Practice;Mar2013, Vol. 9 Issue 2, following p92 

    Purpose: National guidelines recommend adjuvant intravesical Bacillus Calmette-Guérin (BCG) therapy for higher-risk non-muscle-invasive bladder cancer (NMIBC). Although a survival benefit has not been demonstrated, randomized trials have shown reduced recurrence and delayed progression after...

  • Influence of Body Mass Index on Survival in Veterans With MultipleMyeloma. BEASON, TRACEY S.; SU-HSIN CHANG; SANFILIPPO, KRISTEN M.; SUHONG LUO; COLDITZ, GRAHAM A.; VIJ, RAVI; TOMASSON, MICHAEL H.; DIPERSIO, JOHN F.; STOCKERL-GOLDSTEIN, KEITH; GANTI, ARUN; WILDES, TANYA; CARSON, KENNETH R. // Oncologist;Oct2013, Vol. 18 Issue 10, preceding p1074 

    Purpose. We investigated the association between body mass index (BMI) at the time of multiple myeloma (MM) diagnosis and overall survival in a cohort of patients within the Veterans Health Administration system. We also evaluated the association between weight loss in the year prior to...

  • Is the effect of non-invasive ventilation on survival in amyotrophic lateral sclerosis age-dependent? Siirala, Waltteri; Aantaa, Riku; Olkkola, Klaus T.; Saaresranta, Tarja; Vuori, Arno // BMC Palliative Care;2013, Vol. 12 Issue 1, p23 

    Background: Hypoventilation due to respiratory muscle atrophy is the most common cause of death as a result of amyotrophic lateral sclerosis (ALS). Patients aged over 65 years and presenting bulbar symptoms are likely to have a poorer prognosis. The aim of the study was to assess the possible...

  • Psychological distress and risk of long-term disability: population-based longitudinal study. Rai, Dheeraj; Kosidou, Kyriaki; Lundberg, Michael; Araya, Ricardo; Lewis, Glyn; Magnusson, Cecilia // Journal of Epidemiology & Community Health;Jul2012, Vol. 66 Issue 7, p586 

    Background Common mental disorders are known to cause long-term disability, although not much is known about long-term consequences of milder forms of psychological distress. Objective To investigate the association between increasing levels of psychological distress and 5-year risk of long-term...

  • Risk of in-hospital mortality following emergency department admission: Results from the geriatric EDEN cohort study. Launay, C.; Annweiler, C.; Decker, L.; Kabeshova, A.; Fantino, B.; Beauchet, Olivier // Journal of Nutrition, Health & Aging;Jan2014, Vol. 18 Issue 1, p83 

    Objective: To determine whether being admitted to emergency department (ED) for social disorders may predict a higher risk of in-hospital mortality among older inpatients. Design: Prospective cohort study (mean follow-up: 9.1±10.0 days). Setting: Angers University Hospital, France....

  • Diabetes Mellitus Is Associated with Increased Mortality in Patients Receiving Curative Therapy for Hepatocellular Carcinoma. WEN-YI SHAU; YU-YUN SHAO; YI-CHUN YEH; ZHONG-ZHE LIN; KUO, RAYMOND; CHIH-HUNG HSU; CHIUN HSU; ANN-LII CHENG; MEI-SHU LAI // Oncologist;Jun2012, Vol. 17 Issue 6, p856 

    Background. Diabetes mellitus (DM) is closely associated with hepatocarcinogenesis. This study explores the prognostic impact ofDMin patients who received curative therapy for localized hepatocellular carcinoma (HCC). Methods. Patients who had been diagnosed with stage I or II HCC in 2003 and...

  • The Palliative Index: Predicting Outcomes of Emergent Surgery in Patients with Cancer. Roses, Robert E.; Tzeng, Ching-Wei D.; Ross, Merrick I.; Fournier, Keith F.; Abbott, Daniel E.; You, Y. Nancy // Journal of Palliative Medicine;Jan2014, Vol. 17 Issue 1, p37 

    Background: The role of emergent palliative surgery in the setting of advanced malignancy remains a subject of controversy. Objective: The purpose of this study was to identify clinical predictors of outcome in patients with cancer who undergo nonelective abdominal surgery. Setting/Subjects:...

  • Impact of Molecular Alterations and Targeted Therapy in Appendiceal Adenocarcinomas. S. RAGHAV, KANWAL P.; SHETTY, ADITYA V.; A. KAZMI, SYED M.; NIANXIANG ZHANG; MORRIS, JEFFREY; TAGGART, MELISSA; FOURNIER, KEITH; ROYAL, RICHARD; MANSFIELD, PAUL; ENG, CATHY; WOLFF, ROBERT A.; OVERMAN, MICHAEL J. // Oncologist;Dec2013, Vol. 18 Issue 12, preceding p1271 

    Background. Appendiceal adenocarcinomas (AAs) are rare and this has limited their molecular understanding. The purpose of our study was to characterize the molecular profile of AA and explore the role of targeted therapy against cyclooxygenase- 2 (COX-2) and epidermal growth factor receptor...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics