TITLE

Enhanced fluorescence emission using a photonic crystal coupled to an optical cavity

AUTHOR(S)
Pokhriyal, Anusha; Lu, Meng; Chaudhery, Vikram; George, Sherine; Cunningham, Brian T.
PUB. DATE
June 2013
SOURCE
Applied Physics Letters;6/3/2013, Vol. 102 Issue 22, p221114
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
All fluorescent assays would benefit from greater signal-to-noise ratios (SNRs), which enable detection of disease biomarkers at lower concentrations for earlier disease diagnosis and detection of genes that are expressed at the lowest levels. Here, we report an approach to enhance fluorescence in which surface adsorbed fluorophore-tagged biomolecules are excited on a photonic crystal surface that is coupled to an underlying Fabry-Perot type cavity through a gold mirror reflector beneath the photonic crystal. This approach leads to 6× increase in signal-to-noise ratio of a dye labeled polypeptide compared to ordinary photonic crystal enhanced fluorescence.
ACCESSION #
88041260

 

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