TITLE

Microwave-assisted synthesis of optically active N-substituted 2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-ones and -thiazin-3(4H)-ones via Smiles rearrangement

AUTHOR(S)
Li-Juan Meng; Hua Zuo; Zhu-Bo Li; Dupati, Gautam; Kiwan Jang; Gichuel Moon; Bao-Xiang Zhao; Jun-Ying Miao; Dong-Soo Shin
PUB. DATE
May 2013
SOURCE
Research & Reports in Medicinal Chemistry;May2013, p11
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Optically active N-substituted-2-methyl-2H-benzo[b][1,4]oxazin-3(4H)-ones and N-substituted-2-methyl-2H-benzo[b][1,4]thiazin-3(4H)-ones with potential synthetic and pharmacological interest were prepared via Smiles rearrangement using microwave irradiation in one-pot from inexpensive (S)-2-chloropropionic acid.
ACCESSION #
88036043

 

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