TITLE

Radical scavenging and In-Vitro Hemolytic Activity of Aqueous Extracts of Selected Acacia Species

AUTHOR(S)
Sulaiman, C. T.; Gopalakrishnan, V. K.
PUB. DATE
March 2013
SOURCE
Journal of Applied Pharmaceutical Science;Mar2013, Vol. 3 Issue 3, p109
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aqueous extracts of three Acacia species were screened for their free radical scavenging and in vitro hemolytic activity. The total phenolic content was also determined in all the three species. The total phenolics were estimated spectrophotometrically based on the reduction of phosphomolybdate ion of Folin-Ciocalteu reagent and was expressed as milligram equivalent of Gallic acid. The radical scavenging activity was evaluated by DPPH assay. Acacia nilotica showed maximum radical scavenging activity with EC50 12.5. Hemolytic activity of the aqueous extracts was screened against normal human erythrocytes. Aqueous extract of A. leucophloea possessed minimum hemolytic activity where as A.nilotica showed highest hemolytic activity
ACCESSION #
88017328

 

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