TITLE

Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line

AUTHOR(S)
Prabhu, Velliangiri; Ravi, Subban
PUB. DATE
September 2012
SOURCE
Journal of Applied Pharmaceutical Science;Sep2012, Vol. 2 Issue 9, p132
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The essential oil from the fresh leaves of Chromolaena odorata (Asteraceae) (L.) R.M. King & H. Rob. was obtained by hydro distillation. From the essential oil the compound (I) a triterpene derivative was isolated by column chromatography and it was characterized by IR, ¹H-NMR, 13C-NMR and MS spectral data. It was screened for cytotoxicity against HepG2 by MTT assay. It showed significant cytotoxicity with IC50 value of 206.7 µg/ml towards HepG2 cancer cell line.
ACCESSION #
88017154

 

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