The occurrence of cerebrovascular atherosclerosis in Alzheimer's disease patients

Jing Yuan; Ge Wen; Yingjia Li; Changxing Liu
May 2013
Clinical Interventions in Aging;May2013, Vol. 8, p581
Academic Journal
Background: Both Alzheimer's disease (AD) and cerebrovascular atherosclerosis (CA) contributed to dementia in an aged population. Whether they share the same mechanism is unknown. Aim: Our goal was to explore the occurrence rates of CA in AD patients. Method: Here we examined the degree of CA in different groups of AD patients with contrast angiography. Ninety-three AD patients were recruited to the present study. Contrast computed tomography scanning and contrast angiography were performed for CA analyses. Result: We found that the cerebrovascular plaques were common in AD patients, which was partly correlated with the severity of AD (as determined by cognitive decline). Conclusion: We concluded that vascular dementia may partly correlate with AD pathology


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