TITLE

Piper Guineense: A Possible Alternative Treatment for Multidrug Resistant EHEC

AUTHOR(S)
Omonigbehin, Emmanuel Adedayo; Deji.-Agboola, Mope A.; Ezeh, Abimbola Rashidat; Smith, Stella I.; Bamidele, Moses; Fesobi, Toun Wuraola; Adenike, Fowora Muinah; Kayode, Akindele Samuel; Oluwadun, Afolabi
PUB. DATE
February 2013
SOURCE
International Journal of Applied Science & Technology;Feb2013, Vol. 3 Issue 2, p55
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The susceptibility of sixteen (16) Enterohaemorrhagic Escherichia coli 0157: H7 isolates to conventional antibiotics and extracts of P. guineensewas compared using agar diffusion method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract was determined using broth dilution and agar diffusion methods respectively. The result of the susceptibility test showed that majority of the EHEC isolates were resistant to 63.64% of the antibiotics used, showing multidrug resistance. The antibacterial assay of P. gunineenserevealed inhibition against all the isolates (100%) with MIC (200mg/ml) and MBC (400mg/ml).
ACCESSION #
88011495

 

Related Articles

  • Characterization of Colicinogenic Escherichia coli Strains Inhibitory to Enterohemorrhagic Escherichia coli. Schamberger, Gerry P.; Diez-Gonzalez, Francisco // Journal of Food Protection;Mar2004, Vol. 67 Issue 3, p486 

    A previously identified set of anti-Escherichia coli O157:H7 colicinogenic E. coli were characterized to assess the suitability of these isolates as a pmharvest food safety intervention in cattle. This collection of 23 E. coli strains were screened for virulence factors, antibiotic resistance,...

  • Efficacy of Chemical Interventions against Escherichia coli O157:H7 and Multidrug-Resistant and Antibiotic-Susceptible Salmonella on Inoculated Beef Trimmings. GEORNARAS, IFIGENIA; HUA YANG; MOSCHONAS, GALATIOS; NUNNELLY, MATTHEW C.; BELK, KEITH E.; NIGHTINGALE, KENDRA K.; WOERNER, DALE R.; SMITH, GARY C.; SOFOS, JOHN N. // Journal of Food Protection;Nov2012, Vol. 75 Issue 11, p1960 

    Studies were conducted to compare the decontamination efficacy of six chemical treatments against Escherichia coli O157:H7 and multidrug-resistant and antibiotic-susceptible Salmonella inoculated on beef trimmings. The inocula, comprising four-strain mixtures of rifampin-resistant E. coli...

  • Antibiotic Resistance and Hypermutability of Escherichia coil O157 from Feed lot Cattle Treated with Growth-Promoting Agents. Lefebvre, Brigitte; Diarra, Moussa S.; Giguère, Karine; Roy, Gabriel; Michaud, Sophie; Malouini, Françis // Journal of Food Protection;Nov2005, Vol. 68 Issue 11, p2411 

    In a longitudinal study (165 days), we investigated the effect of growth-promoting agents (monensin and trenbolone acetate-estradiol) and an antibiotic (oxytetracycline) on the incidence in feedlot steers of Escherichia coli O157, including antibiotic-resistant and hypermutable isolates. Eighty...

  • Inhibition of Growth of Highly Resistant Bacterial and Fungal Pathogens by a Natural Product. Hafidh, Rand R.; Abdulamir, Ahmed S.; Se Vern, Law; Bakar, Fatimah Abu; Abas, Faridah; Jahanshiri, Fatemeh; Sekawi, Zamberi // Open Microbiology Journal;2011, Vol. 5, p96 

    The continuous escalation of resistant bacteria against a wide range of antibiotics necessitates discovering novel unconventional sources of antibiotics. B. oleracea L (red cabbage) is health-promoting food with proven anticancer and anti-inflammatory activities. However, it has not been...

  • Drug-resistant Escherichia coli, Rural Idaho. Hannah, Elizabeth L.; Angulo, Frederick J.; Johnson, James R.; Haddadin, Bassam; Williamson, Jacquelyn; Samore, Matthew H. // Emerging Infectious Diseases;Oct2005, Vol. 11 Issue 10, p1614 

    Stool carriage of drug-resistant Escherichia coli in home-living residents of a rural community was examined. Carriage of nalidixic acid-resistant E. coli was associated with recent use of antimicrobial agents in the household. Household clustering of drug-resistant E. coli was observed. Most...

  • Sequences of Two Related Multiple Antibiotic Resistance Virulence Plasmids Sharing a Unique IS26-Related Molecular Signature Isolated from Different Escherichia coli Pathotypes from Different Hosts. Venturini, Carola; Hassan, Karl A.; Roy Chowdhury, Piklu; Paulsen, Ian T.; Walker, Mark J.; Djordjevic, Steven P. // PLoS ONE;Nov2013, Vol. 8 Issue 11, p1 

    Enterohemorrhagic Escherichia coli (EHEC) and atypical enteropathogenic E. coli (aEPEC) are important zoonotic pathogens that increasingly are becoming resistant to multiple antibiotics. Here we describe two plasmids, pO26-CRL125 (125 kb) from a human O26:H- EHEC, and pO111-CRL115 (115kb) from a...

  • Structure-based discovery of antibacterial drugs. Simmons, Katie J.; Chopra, Ian; Fishwick, Colin W. G. // Nature Reviews Microbiology;Jul2010, Vol. 8 Issue 7, p501 

    The modern era of antibacterial chemotherapy began in the 1930s, and the next four decades saw the discovery of almost all the major classes of antibacterial agents that are currently in use. However, bacterial resistance to many of these drugs is becoming an increasing problem. As such, the...

  • Genetic transfer ability broadens CRKP threat.  // Hospital Infection Control & Prevention;May2009, Vol. 36 Issue 5, p54 

    The article describes a specific aspect of the threat presented by carbapenem-resistant Klebsiella pneumoniae (CRKP), namely the threat of the transfer of genetic material that contains its mechanism of resistance to Escherichia coli. It states that the transfer of the Klebsiella pneumoniae...

  • Fecal Shedding of Escherichia coli O157, Salmonella, and Campylobacter in Swiss Cattle at Slaughter. Al-Saigh, H.; Zweifel, C.; Blanco, J.; Blanco, J.E.; Blanco, M.; Usera, M.A.; Stephan, R. // Journal of Food Protection;Apr2004, Vol. 67 Issue 4, p679 

    Fecal samples from 2,930 slaughtered healthy cattle were examined with the following goals: (i) to monitor the shedding of Escherichia coli O157, Salmonella, and Campylobacter in cattle; and (ii) to further characterize the isolated strains. The percentage of the 2,930 samples that tested...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics