Piper Guineense: A Possible Alternative Treatment for Multidrug Resistant EHEC

Omonigbehin, Emmanuel Adedayo; Deji.-Agboola, Mope A.; Ezeh, Abimbola Rashidat; Smith, Stella I.; Bamidele, Moses; Fesobi, Toun Wuraola; Adenike, Fowora Muinah; Kayode, Akindele Samuel; Oluwadun, Afolabi
February 2013
International Journal of Applied Science & Technology;Feb2013, Vol. 3 Issue 2, p55
Academic Journal
The susceptibility of sixteen (16) Enterohaemorrhagic Escherichia coli 0157: H7 isolates to conventional antibiotics and extracts of P. guineensewas compared using agar diffusion method. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract was determined using broth dilution and agar diffusion methods respectively. The result of the susceptibility test showed that majority of the EHEC isolates were resistant to 63.64% of the antibiotics used, showing multidrug resistance. The antibacterial assay of P. gunineenserevealed inhibition against all the isolates (100%) with MIC (200mg/ml) and MBC (400mg/ml).


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