Correlates between HIV/AIDS Antibody with some Immuno-Hematological Variables of Infected Subjects in Niger Delta Communities

Azuonwu, O.; Frank-Peterside; Erhabor, O.
August 2012
Journal of Applied Pharmaceutical Science;Aug2012, Vol. 2 Issue 8, p85
Academic Journal
The study tend to uncover the epidemiological trend and association of HIV/AIDS with some immuno-hematological profile of infected subjects in Niger Delta. A total of 1000 subjects, made up of 464 males (46.4%) and 536 females (53.6%) were screened. HIV antibodies were detected using "Determine" (Abbott Laboratories, Japan), Start -Pak (Chembio Diagnostics, USA) and SD Bioline HIV-1/2 kits (Standard Diagnostics, Korea).Out of this number, 107(10.7%) were sero-positive. The PCV of HIV positive subjects ranged between 24.00 and 48.00% (32.94±0.53),HB ranged between 8.00 and 16.00g/dl (10.95± 0.18) while WBC counts ranged between 3.30 and 16.30 Mm³(7.76 ±0.30). However, CD4 counts ranged between 210.00 and 937.00µl, with a mean of 480.55 (±13.44). At P<0.01; the PCV correlated positively with HB(r=0.999) and negatively with WBC (r = -0.303), while HB correlated negatively with WBC(r=-0.306). Conversely, CD4 counts did not correlate with any of the parameters. The need for frequent monitoring of the impact of HIV/AIDS on the immunological profile of infected groups in Niger Delta is strongly encourage. This will prevent anemia and other hematological problems.


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