Effect of ketorolac on the prevention of emergence agitation in children after sevoflurane anesthesia

Deokkyu Kim; Doo, A. Ram; Hyungsun Lim; Son, Ji-Seon; Lee, Jun-Rae; Han, Young-Jin; Seonghoon Ko
March 2013
Korean Journal of Anesthesiology;Mar2013, Vol. 64 Issue 3, p240
Academic Journal
Background: The purpose of this study was to evaluate the effects of ketorolac on the incidence and severity of emergence agitation in children recovering from sevoflurane anesthesia. Methods: Eighty-five children aged 3 to 7 years were randomly assigned to the control group or the ketorolac group (1 mg/kg ketorolac). The children were evaluated by the Pediatric Anesthesia Emergence Delirium Scale and a four-point agitation scale. Results: The median agitation scores did not differ significantly between the two groups. The overall incidence of emergence agitation was similar in the two groups (41% in the control group vs. 32% in the ketorolac group, P = 0.526). The number of children who received rescue drugs for treatment of emergence agitation was not significantly different between the two groups. Conclusions: The administration of 1 mg/kg of ketorolac is not effective in decreasing the incidence and severity of emergence agitation in children aged 3 to 7 years after sevoflurane anesthesia.


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