MicroRNA-215 inhibits relapse of colorectal cancer patients following radical surgery

Li, Shan; Gao, Jing; Gu, Jin; Yuan, Jiajia; Hua, Dong; Shen, Lin
June 2013
Medical Oncology;Jun2013, Vol. 30 Issue 2, p1
Academic Journal
No abstract available.


Related Articles

  • MicroRNA-93 inhibits tumor growth and early relapse of human colorectal cancer by affecting genes involved in the cell cycle. Yang, I-Ping; Tsai, Hsiang-Lin; Hou, Ming-Feng; Chen, Ku-Chung; Tsai, Pei-Chien; Huang, Szu-Wei; Chou, Wen-Wen; Wang, Jaw-Yuan; Juo, Suh-Hang Hank // Carcinogenesis;Aug2012, Vol. 33 Issue 8, p1522 

    Purpose: Colorectal cancer (CRC) is associated with high recurrence and mortality. Because deregulation of microRNAs is associated with CRC development and recurrence, the expression levels of microRNAs can be a simple and reliable biomarker to detect postoperative early relapse, thereby helping...

  • MicroRNA and Colorectal Cancer. Yang, Linda; Belaguli, Narasimhaswamy; Berger, David H. // World Journal of Surgery;Apr2009, Vol. 33 Issue 4, p638 

    MicroRNAs are small 19 to 22 nucleotide sequences of RNA that participate in the regulation of cell differentiation, cell cycle progression, and apoptosis. MicroRNAs act much like small interfering RNA, annealing with RISC, to cleave messenger RNA, and microRNAs exert translational inhibition...

  • The Functional Significance of MicroRNA-29c in Patients with Colorectal Cancer: A Potential Circulating Biomarker for Predicting Early Relapse. Yang, I-Ping; Tsai, Hsiang-Lin; Huang, Ching-Wen; Huang, Ming-Yii; Hou, Ming-Feng; Juo, Suh-Hang Hank; Wang, Jaw-Yuan // PLoS ONE;Jun2013, Vol. 8 Issue 6, p1 

    Background: The recurrence of colorectal cancer (CRC) is frequent within the first year of curative resection surgery and may be unavoidable. microRNAs have been suggested to play roles in carcinogenesis and cancer recurrence. We recently identified microRNA-29c (miRNA-29c) as a predictor of...

  • Comparison of microRNA expression levels between initial and recurrent glioblastoma specimens. Ilhan-Mutlu, Aysegül; Wöhrer, Adelheid; Berghoff, Anna; Widhalm, Georg; Marosi, Christine; Wagner, Ludwig; Preusser, Matthias // Journal of Neuro-Oncology;May2013, Vol. 112 Issue 3, p347 

    Glioblastoma is the most frequent primary brain tumour in adults. Recent therapeutic advances increased patient's survival, but tumour recurrence inevitably occurs. The pathobiological mechanisms involved in glioblastoma recurrence are still unclear. MicroRNAs are small RNAs proposed o have...

  • Poster Session I (Arlington-Berkeley): Biomarkers.  // Journal of Extracellular Vesicles;2013, Vol. 2, p22 

    The article presents abstracts on topics related to biomarkers which include detection of antibodies recognizing melanoma exosomes, detection of circulating microRNA in patients with colorectal cancer, and transcription factors in circulating microvesicles from cancer patients.

  • Clinicopathological Significance of MicroRNA-214 in Gastric Cancer and Its Effect on Cell Biological Behaviour. Wang, Ya-Wen; Shi, Duan-Bo; Chen, Xu; Gao, Chao; Gao, Peng // PLoS ONE;Mar2014, Vol. 9 Issue 3, p1 

    Accumulating evidence indicates that numerous microRNAs are involved in the tumorigenesis and progression of gastric cancer, while the clinical significance of microRNA-214 in gastric cancer is poorly understood and the exact role of microRNA-214 in gastric cancer remains obscure. In the present...

  • EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. G. J. Weiss; L. T. Bemis; E. Nakajima; M. Sugita; D. K. Birks; W. A. Robinson; M. Varella-Garcia; P. A. Bunn; J. Haney; B. A. Helfrich; H. Kato; F. R. Hirsch; W. A. Franklin // Annals of Oncology;Jun2008, Vol. 19 Issue 6, p1053 

    Background: Allelic loss in chromosome 3p is one of the most frequent and earliest genetic events in lung carcinogenesis. We investigated if the loss of microRNA-128b, a microRNA located on chromosome 3p and a putative regulator of epidermal growth factor receptor (EGFR), correlated with...

  • miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. Silber, Joachim; Lim, Daniel A.; Petritsch, Claudia; Persson, Anders I.; Maunakea, Alika K.; Yu, Mamie; Vandenberg, Scott R.; Ginzinger, David G.; James, C. David; Costello, Joseph F.; Bergers, Gabriele; Weiss, William A.; Alvarez-Buylla, Arturo; Hodgson, J. Graeme // BMC Medicine;2008, Vol. 6, Special section p1 

    Background: Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the molecular and cellular mechanisms that drive GBM formation are required to improve patient outcome. MicroRNAs are...

  • Cytoreductive surgery (CR) followed by hyperthermic intraperitoneal chemotherapy (HIPEC): a chance of survival for patients with advanced colorectal cancer. Bartoş, Adrian; Monica Bartos, Dana; Breazu, Caius; Hosu, Miana; Stoian, Raluca; Iancu, Cornel // Journal of Gastrointestinal & Liver Diseases;Sep2015, Vol. 24 Issue 3, p392 

    The article demonstrates the cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy in patients with advanced colorectal cancer.

  • Detection of microRNA-200b may predict the inhibitory effect of gefitinib on non-small cell lung cancer and its potential mechanism. ZHIWU LIU; LIQIONG YAO; BANGYUN TAN; LI LI; BAOJIN CHEN // Oncology Letters;Dec2016, Vol. 12 Issue 6, p5349 

    The present study aimed to investigate the association and underlying mechanisms between microRNA-200b level and the inhibitory effect of gefitinib on non-small cell lung cancer. In total, 100 patients (43 males and 57 females; median age, 63 years) with advanced non-small cell lung cancer...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics