TITLE

Biotin-streptavidin detection with a graphene-oxide supported radio-frequency resonator

AUTHOR(S)
Seo Yoon, Hyong; Lim, Juhwan; Uk Son, Sang; Kim, Duck-Hwan; Song, Insang; Chan Jun, Seong
PUB. DATE
May 2013
SOURCE
Applied Physics Letters;5/13/2013, Vol. 102 Issue 19, p193701
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The detection of biotin-streptavidin binding was demonstrated by the resonance frequency measurement of a simple resonance circuit using graphene oxide dielectric. The resonance frequency was decreased to the lower frequency range as biotin and streptavidin were bound to the graphene oxide film. Graphene oxide dielectric provides dual advantages including quality-factor enhancement and high affinity for bio sensing. It was revealed that an increase in capacitance of the graphene oxide sheet was mainly responsible for the resonance frequency shift. The sensitivity to the capacitance change in the frequency-based detection technique can enable the advanced biosensing applications using graphene oxide sheet.
ACCESSION #
87655995

 

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