No Working Kinase, but ErbB3 Acquires Oncogenic Mutations

Breindl, Anette
May 2013
BioWorld Today;5/15/2013, Vol. 24 Issue 93, p1
The article discusses the avian erythroblastosis oncogene B (ErbB) family of receptor tyrosine kinases. It informs that epidermal growth factor receptor (EGRF), the better-known alias of ErbB1, is the target of drugs such as Tarceva, Iressa,Vectibix and Erbitux. The article also mentions that researchers have presented evidence that ErbB3, at third ErbB family member, can also acquire activating for oncogenic mutations.


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