TITLE

Immune Responses of a Native and an Invasive Bird to Buggy Creek Virus (Togaviridae: Alphavirus) and Its Arthropod Vector, the Swallow Bug (Oeciacus vicarius)

AUTHOR(S)
Fassbinder-Orth, Carol A.; Barak, Virginia A.; Brown, Charles R.
PUB. DATE
February 2013
SOURCE
PLoS ONE;Feb2013, Vol. 8 Issue 2, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Invasive species often display different patterns of parasite burden and virulence compared to their native counterparts. These differences may be the result of variability in host-parasite co-evolutionary relationships, the occurrence of novel host-parasite encounters, or possibly innate differences in physiological responses to infection between invasive and native hosts. Here we examine the adaptive, humoral immune responses of a resistant, native bird and a susceptible, invasive bird to an arbovirus (Buggy Creek virus; Togaviridae: Alphavirus) and its ectoparasitic arthropod vector (the swallow bug; Oeciacus vicarius). Swallow bugs parasitize the native, colonially nesting cliff swallow (Petrochelidon pyrrhonota) and the introduced house sparrow (Passer domesticus) that occupies nests in cliff swallow colonies. We measured levels of BCRV-specific and swallow bug-specific IgY levels before nesting (prior to swallow bug exposure) and after nesting (after swallow bug exposure) in house sparrows and cliff swallows in western Nebraska. Levels of BCRV-specific IgY increased significantly following nesting in the house sparrow but not in the cliff swallow. Additionally, house sparrows displayed consistently higher levels of swallow bug-specific antibodies both before and after nesting compared to cliff swallows. The higher levels of BCRV and swallow bug specific antibodies detected in house sparrows may be reflective of significant differences in both antiviral and anti-ectoparasite immune responses that exist between these two avian species. To our knowledge, this is the first study to compare the macro- and microparasite-specific immune responses of an invasive and a native avian host exposed to the same parasites.
ACCESSION #
87625750

 

Related Articles

  • Comparison of complete polyprotein sequences of two isolates of salmon alphavirus (SAV) type I and their behaviour in a salmonid cell line. Matejusova, Iveta; Lester, Katherine; Li, Ziduo; Bravo, Jimena; Bland, Fiona; Collet, Bertrand // Archives of Virology;Oct2013, Vol. 158 Issue 10, p2143 

    Salmon pancreas disease virus is an alphavirus (family Togaviridae) affecting mainly Atlantic salmon ( Salmo salar L.). Both polyprotein sequences of the Scottish isolate (SAV4640) were determined and compared with those of Irish isolate SAVF93-125. High amino acid sequence similarity (99.4 %)...

  • Host response: Innate mimicry. Molloy, Sheilagh // Nature Reviews Microbiology;May2008, Vol. 6 Issue 5, p329 

    The article highlights a study which has identified a new class of virulence factor that bacterial pathogens use to interfere with Toll-like receptor (TLR) signalling. It relates that the study has identified a TIR-domain containing proteins (Tcp) in Brucella abortus and reveals that bacterial...

  • Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis. Wells, Ryan M.; Jones, Christopher M.; Zhaoyong Xi; Speer, Alexander; Danilchanka, Olga; Doornbos, Kathryn S.; Peibei Sun; Fangming Wu; Changlin Tian; Niederweis, Michael // PLoS Pathogens;Jan2013, Vol. 9 Issue 1, p1 

    Iron is an essential nutrient for most bacterial pathogens, but is restricted by the host immune system. Mycobacterium tuberculosis (Mtb) utilizes two classes of small molecules, mycobactins and carboxymycobactins, to capture iron from the human host. Here, we show that an Mtb mutant lacking the...

  • Innate Immune Detection of Bacterial Virulence Factors Via the NLRC4 Inflammasome. Miao, Edward A.; Warren, Sarah E. // Journal of Clinical Immunology;Jul2010, Vol. 30 Issue 4, p502 

    Cytokine production by innate immune cells is initiated by signaling downstream of pattern recognition receptors, including Toll-like receptors. A subset of cytokines, including IL-1β and IL-18, require post-translational proteolysis before secretion, which provides a second mechanism of...

  • Early antibody response against Mycobacterium avium subspecies paratuberculosis antigens in subclinical cattle. Bannantine, John P.; Bayles, Darrell O.; Waters, W. Ray; Palmer, Mitchell V.; Stabel, Judith R.; Paustian, Michael L. // Proteome Science;2008, Vol. 6, Special section p1 

    Background: Our laboratories have previously reported on the experimental infection of cattle with Mycobacterium avium subsp paratuberculosis (M. paratuberculosis) using an intratonsillar infection model. In addition, we have recently developed a partial protein array representing 92 M....

  • Outer membrane protein P4 is not required for virulence in the human challenge model of Haemophilus ducreyi infection. Janowicz, Diane M.; Zwickl, Beth W.; Fortney, Kate R.; Katz, Barry P.; Bauer, Margaret E. // BMC Microbiology;2014, Vol. 14 Issue 1, p1 

    Background Bacterial lipoproteins often play important roles in pathogenesis and can stimulate protective immune responses. Such lipoproteins are viable vaccine candidates. Haemophilus ducreyi, which causes the sexually transmitted disease chancroid, expresses a number of lipoproteins during...

  • A Sch9 protein kinase homologue controlling virulence independently of the cAMP pathway inCryptococcus neoformans. Wang, Ping; Cox, Gary M.; Heitman, Joseph // Current Genetics;Oct2004, Vol. 46 Issue 5, p247 

    The polysaccharide capsule is one of the established virulence factors inCryptococcus neoformansthat provides a barrier against the host-mediated immune response. Mutation of the gene encoding theSaccharomyces cerevisiaeSch9 protein kinase homologue resulted in cells with enlarged capsules inC....

  • How the Fly Balances Its Ability to Combat Different Pathogens. Chambers, Moria C.; Lightfield, Karla L.; Schneider, David S. // PLoS Pathogens;Dec2012, Vol. 8 Issue 12, p1 

    Health is a multidimensional landscape. If we just consider the host, there are many outputs that interest us: evolutionary fitness determining parameters like fecundity, survival and pathogen clearance as well as medically important health parameters like sleep, energy stores and appetite....

  • Development of vaccines for Candida albicans: fighting a skilled transformer. Cassone, Antonio // Nature Reviews Microbiology;Dec2013, Vol. 11 Issue 12, p884 

    Two univalent subunit vaccines that are based on major virulence traits of Candida albicans have completed Phase I clinical trials in recent years. Although it is hoped that at least one will become the first antifungal vaccine approved for human use, there are some major obstacles to achieving...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics