Determinants of Clinician Knowledge on Aging and HIV/AIDS: A Survey of Practitioners and Policy Makers in Kampala District, Uganda

Obuku, Ekwaro A.; Parikh, Sujal M.; Nankabirwa, Victoria; Kakande, Nelson I.; Mafigiri, David K.; Mayanja-Kizza, Harriet; Kityo, Cissy M.; Mugyenyi, Peter N.; Salata, Robert A.
February 2013
PLoS ONE;Feb2013, Vol. 8 Issue 2, p1
Academic Journal
Objective: The HIV/AIDS epidemic has evolved with an increasing burden in older adults. We assessed for knowledge about aging and HIV/AIDS, among clinicians in Kampala district, Uganda. Methods: A cross-sectional survey of 301 clinicians complemented by 9 key-informant interviews between May and October 2011. Data was analyzed by multivariable logistic regression for potential determinants of clinician knowledge about HIV/AIDS in older adults, estimating their adjusted Odds Ratios (aOR) and 95% confidence intervals (95% CI) using Stata 11.2 software. Results: Two-hundred and sixty-two questionnaires (87.7%) were returned. Respondents had a median age of 30 years (IQR 27–34) and 57.8% were general medical doctors. The mean knowledge score was 49% (range 8.8%–79.4%). Questions related to co-morbidities in HIV/AIDS (non-AIDS related cancers and systemic diseases) and chronic antiretroviral treatment toxicities (metabolic disorders) accounted for significantly lower scores (mean, 41.7%, 95% CI: 39.3%–44%) compared to HIV/AIDS epidemiology and prevention (mean, 65.7%, 95% CI: 63.7%–67.7%). Determinants of clinician knowledge in the multivariable analysis included (category, aOR, 95% CI): clinician age (30–39 years; 3.28∶1.65–9.75), number of persons with HIV/AIDS seen in the past year (less than 50; 0.34∶0.14–0.86) and clinical profession (clinical nurse practitioner; 0.31∶0.11–0.83). Having diploma level education had a marginal association with lower knowledge about HIV and aging (p = 0.09). Conclusion: Our study identified gaps and determinants of knowledge about HIV/AIDS in older adults among clinicians in Kampala district, Uganda. Clinicians in low and middle income countries could benefit from targeted training in chronic care for older adults with HIV/AIDS and long-term complications of antiretroviral treatment.


Related Articles

  • Mortality in the Year Following Antiretroviral Therapy Initiation in HIV-Infected Adults and Children in Uganda and Zimbabwe. Walker, A. Sarah; Prendergast, Andrew J.; Mugyenyi, Peter; Munderi, Paula; Hakim, James; Kekitiinwa, Addy; Katabira, Elly; Gilks, Charles F.; Kityo, Cissy; Nahirya-Ntege, Patricia; Nathoo, Kusum; Gibb, Diana M. // Clinical Infectious Diseases;Dec2012, Vol. 55 Issue 12, p1707 

    In low-income countries, children ≥4 years and adults with low CD4 count have equally high mortality risk in the 3 months after initiation of antiretroviral therapy, similar to that of untreated individuals. Bacterial infections play a major role; targeted interventions could have...

  • Living Situation Affects Adherence to Combination Antiretroviral Therapy in HIV-Infected Adolescents in Rwanda: A Qualitative Study. Mutwa, Philippe R.; Van Nuil, Jennifer Ilo; Asiimwe-Kateera, Brenda; Kestelyn, Evelyne; Vyankandondera, Joseph; Pool, Robert; Ruhirimbura, John; Kanakuze, Chantal; Reiss, Peter; Geelen, Sibyl; Wijgert, Janneke van de; Boer, Kimberly R. // PLoS ONE;Apr2013, Vol. 8 Issue 4, p1 

    Introduction: Adherence to combination antiretroviral therapy (cART) is vital for HIV-infected adolescents for survival and quality of life. However, this age group faces many challenges to remain adherent. We used multiple data sources (role-play, focus group discussions (FGD), and in-depth...

  • Here's how maraviroc and other entry inhibitors work.  // AIDS Alert;Aug2007, Vol. 22 Issue 8, p89 

    The article focuses on how current entry inhibitors, including the antiretroviral maraviroc, target one of the three stages of the entry of HIV into cells according to doctor W. David Hardy of the Cedars-Sinai Medical Center in Los Angeles, California.

  • A third of those in need of antiretrovirals in poor countries can now get them. Zarocostas, John // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;10/2/2010, Vol. 341 Issue 7775, p695 

    The article focuses on the findings of the global report "Towards Universal Access: Scaling Up Priority HIV/AIDS Interventions in the Health Sector--Progress Report 2010," giving particular emphasis on helping people to have access to antiretrovirals.

  • Intrauterine, postnatal growth unaffected by exposure to HIV, antenatal antiretrovirals.  // Infectious Disease News;Feb2014, Vol. 27 Issue 2, p26 

    The article discusses research into the effects of exposure to HIV and antenatal antiretrovirals on infants' intrauterine or early postnatal growth and references a study by J. Jao and colleagues published in a 2014 issue "The Pediatric Infectious Disease Journal."

  • Highly efficient neutralization of human immunodeficiency viruses by plasma from antiretroviral drug treated patients is mediated by IgG fractions. Andrabi, R.; Makhdoomi, M.; Kumar, R.; Bala, M.; Velpandian, T.; Luthra, K. // Retrovirology;2012 Supplement, Vol. 9 Issue Suppl 2, p1 

    An abstract of the conference paper "Highly Efficient Neutralization of Human Immunodeficiency Viruses by Plasma From Antiretroviral Drug Treated Patients Is Mediated by IgG Fractions," by R. Andrabi and colleagues is presented.

  • Is It Time to Treat HIV Elite Controllers with Combined Antiretroviral Therapy? Torre, Donato // Clinical Infectious Diseases;5/15/2010, Vol. 50 Issue 10, p1425 

    A letter to the editor is presented in response to the article related to treatment HIV of with combination antiretroviral therapy (cART) that was published in a previous issue of the periodical is presented.

  • Reply to Torre. Sedaghat, Ahmad R.; Rastegar, Darius A.; O'Connell, Karen A.; Dinoso, Jason B.; Wilke, Claus O.; Blankson, Joel N. // Clinical Infectious Diseases;5/15/2010, Vol. 50 Issue 10, p1425 

    A letter to the editor is presented offering information related to combination antiretroviral therapy (cART) for treating HIV.

  • PRIMARY CARE AND HIV/AIDS.  // HRSA CareAction;Mar2012, p1 

    The article discusses primary clinical care for individuals living with HIV/AIDS. Clinical care is about much more than managing antiretroviral therapy and managing its side effects. Primary care consists of health promotion, disease prevention, health maintenance, counseling and more. Primary...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics