Staphylococcus lugdunensis Cultured from the Amniotic Fluid at Caesarean Section

Marchocki, Zbigniew; Collins, Kevin; Lehane, Eimear; Reilly, Paddy O'; O'Donoghue, Keelin
February 2013
PLoS ONE;Feb2013, Vol. 8 Issue 2, p1
Academic Journal
Staphylococcus lugdunensis is a virulent coagulase-negative staphylococcus. It behaves like and can be mistaken in culture for Staphylococcus aureus. While originally thought to be a skin commensal rarely responsible for opportunistic infection, it was rapidly established as a significant human pathogen. It has been mainly associated with native and prosthetic valve endocarditis, osteomyelitis, and skin and soft tissue cellulitis, but has also been reported as a cause of fasciitis as well as peritonitis. Staphylococcus lugdunensis has been reported as a cause of endometritis but has not been previously isolated from amniotic fluid. Here, amniotic fluid samples were collected in the course of a larger study on amniotic fluid bacteriology, with prior ethical approval and informed patient consent. Amniotic fluid was obtained at Caesarean Section by direct needle aspiration from the intact amnion. Analysis with Staphylococcal API test kits led to identification of Staphylococcus lugdunensis in two cases. The clinical significance of the finding in these reported cases is undetermined. Staphylococcus lugdunensis has been shown to be a cause of serious and potentially fatal morbidities, but this is the first report of its culture from amniotic fluid. As caesarean delivery is accepted as the single most important factor associated with post-partum infectious complications in both mother and neonate, the identification of this pathogen is a new concern.


Related Articles

  • Determination of some Virulence Factors in Staphylococcus Spp. Isolated from Various Clinical Samples. Türkyilmaz, Süheyla; Kaya, Osman // Turkish Journal of Veterinary & Animal Sciences;2006, Vol. 30 Issue 1, p127 

    The objectives of this study were to identify staphylococci isolated from different animal clinical samples, to examine some of the virulence factors in the isolates, to determine relationships between these virulence factors and coagulase positive Staphylococcus (CoPS)/coagulase negative...

  • Determining the Presence of Superantigens in Coagulase Negative Staphylococci from Humans. Stach, Christopher S.; Vu, Bao G.; Schlievert, Patrick M. // PLoS ONE;11/23/2015, Vol. 10 Issue 11, p1 

    Superantigens (SAgs) are important virulence factors in S. aureus. Recent studies identified their presence in animal coagulase-negative staphylococci (CNS). The emergence of human-associated SAg+ CNS would mark a prodigious shift in virulence capabilities. We examined CNS isolates from healthy...

  • Does reduced liquor volume carry any prognostic significance in normal term pregnancies? Zboun, Ahmed // Middle East Journal of Internal Medicine;Nov2012, Vol. 5 Issue 6, p33 

    Objectives: To study the clinical significance of reduced amniotic fluid volume in low risk term singleton pregnancies. Materials and Methods: In this case controlled study we prospectively studied 220 term singleton pregnancies, at the Department of Obstetrics and Gynecology in Kings Hussein...

  • Impact of amniotic fluid volume on perinatal outcome.  // American Family Physician;1/1/1996, Vol. 53 Issue 1, p344 

    Discusses the article `The impact of amniotic fluid volume assessed intrapartum on perinatal outcome,' by C. Baron et al, published in `American Journal of Obstetrics and Gynecology.' Presence of oligohydramnios and risk of cesarean delivery; Incidence of meconium-stained amniotic fluid;...

  • A Possible Mechanism for Energy between Antifungal Therapy and Immune Defenses. Stevens, David A. // Journal of Infectious Diseases;7/15/2008, Vol. 198 Issue 2, p159 

    The article offers information on various methods used to investigate the pathogenesis of Staphylococcus epidermidis, a leading cause of hospital-acquired device-related infections. Advanced detection techniques such as bioluminescence imaging (BLI) use a highly optical biophotonic camera and...

  • Once a caesarean always a caesarean?  // Australian Parents;Jun/Jul2000, Issue 116, p45 

    Focuses on studies which challenge the assumption that once a woman had a caesarian section she will always have to have one.

  • cesarean-obtained barrier-sustained.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p414 

    An encyclopedia entry for "cesarean-obtained barrier-sustained (COBS)," which refers to animals delivered sterilely by cesarean section and maintained in sanitized environment, is presented.

  • High Cesarean Section Rates In Brazil Result in Large Part From Nonclinical Factors. Estrin, D. // International Family Planning Perspectives;Mar2000, Vol. 26 Issue 1, p47 

    Links high cesarean section rates in Brazil to non-clinical factors. Higher risks for cesarean section among women aged 20 and older; Number of living children; Mothers' experiencing of a stillbirth.

  • Persistent coagulase-negative staphylococci bacteremia in very-low-birth-weight infants. Linder, Nehama; Hernandez, Adriana; Amit, Limor; Klinger, Gil; Ashkenazi, Shai; Levy, Itzhak // European Journal of Pediatrics;Aug2011, Vol. 170 Issue 8, p989 

    This study sought to expand current knowledge on the clinical and epidemiological characteristics of persistent coagulase-negative Staphylococcus (CoNS) bacteremia in very-low-birth-weight (VLBW) infants. Background and disease-related data were collected prospectively on 143 VLBW infants...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics