Poverty, maltreatment and attention deficit hyperactivity disorder

Webb, Elspeth
June 2013
Archives of Disease in Childhood;Jun2013, Vol. 98 Issue 6, p397
Academic Journal
The article focuses on the attention deficit hyperactivity disorder (ADHD) of children. It states that the disorder has adverse health, social and educational outcomes. It highlights the inattentive and hyperactive subtypes of ADHD. It discusses the genetic and epigenetic factors involved in ADHD including monioamine oxidase A (MAOA) and modification of DNA-binding proteins. It mentions the problems associated with diagnosis, management and research on the disorder.


Related Articles

  • Chd5 orchestrates chromatin remodeling during spermiogenesis. Wangzhi Li; Sang-Yong Kim; Ming Zhao; Meistrich, Marvin; Mills, Alea // Epigenetics & Chromatin;2013, Vol. 6 Issue S1, p1 

    A conference paper about the epigenetic remodeling during spermiogenesis is presented. It informs that the paper was discussed at the "Epigenetics and Chromatin: Interactions and processes" conference which was held in Boston, Massachusetts from March 11-13, 2013. The paper further informs about...

  • Variability in micro RNA (miRNA) abundance, speciation and complexity amongst different human populations and potential relevance to Alzheimer's disease (AD). Lukiw, Walter J. // Frontiers in Cellular Neuroscience;Aug2013, Vol. 7, p1 

    The author discusses the variability and potential relevance of microRNA or miRNA to Alzheimer's disease (AD). The author explains the vast variability in gene expression patterns in cells and tissues from different human populations with the miRNA abundance and speciation of a small family of...

  • Precision genetic modifications: a new era in molecular biology and crop improvement. Fichtner, Franziska; Urrea Castellanos, Reynel; Ülker, Bekir // Planta;Apr2014, Vol. 239 Issue 4, p921 

    Recently, the use of programmable DNA-binding proteins such as ZFP/ZFNs, TALE/TALENs and CRISPR/Cas has produced unprecedented advances in gene targeting and genome editing in prokaryotes and eukaryotes. These advances allow researchers to specifically alter genes, reprogram epigenetic marks,...

  • Fidelity Index Determination of DNA Methyltransferases Borgaro, Janine G.; Benner, Nicole; Zhu, Zhenyu // PLoS ONE;May2013, Vol. 8 Issue 5, p1 

    DNA methylation is the most frequent form of epigenetic modification in the cell, which involves gene regulation in eukaryotes and protection against restriction enzymes in prokaryotes. Even though many methyltransferases exclusively modify their cognate sites, there have been reports of those...

  • Optical control of mammalian endogenous transcription and epigenetic states. Konermann, Silvana; Brigham, Mark D.; Trevino, Alexandro E.; Hsu, Patrick D.; Heidenreich, Matthias; Le Cong; Platt, Randall J.; Scott, David A.; Church, George M.; Zhang, Feng // Nature;8/22/2013, Vol. 500 Issue 7463, p472 

    The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causal gene functions in cellular and organismal processes therefore necessitates approaches that enable spatially and temporally precise modulation of...

  • Histone Deacetylase 1 and p300 Can Directly Associate with Chromatin and Compete for Binding in a Mutually Exclusive Manner. Li, Xuehui; Yang, Hui; Huang, Suming; Qiu, Yi // PLoS ONE;Apr2014, Vol. 9 Issue 4, p1 

    Lysine acetyltransferases (KATs) and histone deacetylases (HDACs) are important epigenetic modifiers and dynamically cycled on active gene promoters to regulate transcription. Although HDACs are recruited to gene promoters and DNA hypersensitive sites through interactions with DNA binding...

  • A Molecular Genetic Dissection of the Evolutionarily Conserved N Terminus of Yeast Rad52. Mortensen, Uffe H.; Erdeniz, Naz; Qi Feng; Rothstein, Rodney // Genetics;Jun2002, Vol. 161 Issue 2, p549 

    Examines the genetic dissection of the conserved N Terminus of Rad52 yeast. Content of DNA-binding proteins; Identification of amino acid residues that are important for Rad52 function; Actions of Rad52 protein on lesions.

  • TAL effector-DNA structure. DeFrancesco, Laura // Nature Biotechnology;Feb2012, Vol. 30 Issue 2, p158 

    The article provides information on transcription activator-like (TAL) effectors, a set of Deoxyribonucleic Acid (DNA)-binding proteins that have been embraced by genome engineers because of the simplicity and specificity of their nucleotide binding code.

  • Fusion of AML1/Runx1 to Copine VIII, a novel member of the copine family, in an aggressive acute myelogenous leukemia with t(12;21) translocation. Ramsey, H; Zhang, Do-E; Richkind, K; Burcoglu-O'Ral, A; Hromas, R // Leukemia (08876924);Aug2003, Vol. 17 Issue 8, p1665 

    Normal acute myeloid leukemia (AML)1 interacts with core binding factor CBF beta to function as a heterodimeric transcriptional activator called CBF. CBF is a master regulator of the genetic cascade responsible for myeloid differentiation. Hematopoietic targets for CBF activation include IL-3,...


Read the Article


Sign out of this library

Other Topics