Treatment of high-grade anal dysplasia in high-risk patients: outcome at an urban community health centre

Assoumou, S. A.; Panther, L. A.; Mayer, K. H.
February 2013
International Journal of STD & AIDS;Feb2013, Vol. 24 Issue 2, p134
Academic Journal
Human immunodeficiency (HIV)-infected patients and men who have sex with men (MSM) have a higher rate of high-grade anal intraepithelial neoplasia (HGAIN), a likely precursor to anal cancer. This retrospective study describes the outcome of treating MSM with incident biopsy-proven HGAIN in an urban community health setting with access to outpatient ablation or operative treatment. The main outcome was freedom from HGAIN at follow-up. One hundred and fifty-three met inclusion criteria; 86 (56%) were HIV-infected. Eighty (52%) received outpatient ablation, 49 (61 %) had a follow-up within nine months. Among those, 26 (53%) were free of high-grade disease, 19 (39%) had high-grade disease; and 4 (8%) had unknown grading. In a logistic regression model, a lower extent of anal disease (1 quadrant versus 2, 3 or 4 quadrants) at the time of treatment was significantly associated with a lower probability of high-grade disease (P value 0.04). HGAIN could be managed in a community health setting; however, systems are needed to ensure follow-up care.


Related Articles

  • THE BOYZ DOC. McOWAN, ALAN // BOYZ;9/8/2011, Issue 1045, p47 

    The article offers advice regarding the anal sex experience of a gay man.

  • 'This Will Not Enter Me': Painful Anal Intercourse Among Black Men Who Have Sex with Men in South African Townships. Collier, Kate; Sandfort, Theo; Reddy, Vasu; Lane, Tim // Archives of Sexual Behavior;Feb2015, Vol. 44 Issue 2, p317 

    Little is known about painful receptive anal intercourse (RAI) and its relationship to HIV risk and protective behaviors among men who have sex with men (MSM). The purpose of this study was to identify attributions for and responses to painful RAI among Black MSM in South African townships....

  • Community-Based HIV-1 Early Diagnosis and Risk Behavior Analysis of Men Having Sex with Men in Hong Kong. Liang, Jianguo; Liu, Li; Cheung, Mandy; Lee, Man-Po; Wang, Haibo; Li, Chun-ho; Chan, Chun-Chung; Nishiura, Kenji; Tang, Xian; Tan, Zhiwu; Peng, Jie; Cheung, Ka-Wai; Yam, Wing-Cheong; Chen, Zhiwei // PLoS ONE;Apr2015, Vol. 10 Issue 4, p1 

    The increasing prevalence of HIV-1 among men having sex with men (MSM) calls for an investigation of HIV-1 prevalence and incidence in MSM by early diagnosis to assist with early preventive interventions in Hong Kong. The participants were recruited randomly from MSM communities within a...

  • Panel looks at inequities among gays globally. Hernandez, Peter // Bay Area Reporter;4/25/2013, Vol. 43 Issue 17, p2 

    The article presents information on the discussion by the panel of five speakers on legislation related to health and rights of gay men held at the Global Forum on Men who have sex with men (MSM) and Human Immunodeficiency Virus (HIV) at LGBT Community Centre on April 17 in Oakland in California.

  • Sexual relationships among men who have sex with men in Hanoi, Vietnam: a qualitative interview study. Bengtsson, Linus; Thorson, Anna; Nguyen Thanh, Vu Pham; Allebeck, Peter; Popenoe, Rebecca // BMC Public Health;2013, Vol. 13 Issue 1, p1 

    Background: The prevalence of HIV among men who have sex with men (MSM) in Vietnam's two largest cities, Hanoi and Ho Chi Minh City, may be above 10%. The aim of this study was to explore sexual relationship patterns and experiences among MSM in Hanoi, to inform HIV preventive efforts. Using...

  • Hard-to-reach populations of men who have sex with men and sex workers: a systematic review on sampling methods. Barros, Ana B.; Dias, Sonia F.; Martins, Maria Rosario O. // Systematic Reviews;10/30/2015, Vol. 4, p1 

    Background: In public health, hard-to-reach populations are often recruited by non-probabilistic sampling methods that produce biased results. In order to overcome this, several sampling methods have been improved and developed in the last years. The aim of this systematic review was to identify...


    The article focuses on the Men who have Sex with Men (MSM) Internet Survey Ireland (MISI 2015) report released by healthcare services provider Health Service Executive and Gay Health Network, which reveals that young MSM possess less knowledge about HIV and sexually transmitted infections (STIs).

  • HIV, hepatitis and syphilis prevalence and correlates of condom use during anal sex among men who have sex with men in the Republic of Moldova. Zohrabyan, L; Johnston, L; Scutelniciuc, O; Iovita, A; Todirascu, L; Costin, T; Plesca, V; Cotelnic-Harea, T; Ionascu, G // International Journal of STD & AIDS;May2013, Vol. 24 Issue 5, p357 

    Limited data on HIV prevalence and related risks among men who have sex with men (MSM) exist in the Republic of Moldova. In Chisinau and Balti, 188 and 209, respectively, men who reported having anal or oral sex in the last six months with another man, aged ≥16 years were recruited into a...

  • Factors associated with unprotected anal intercourse among men who have sex with men in Douala, Cameroon. Henry, E.; Marcellin, F.; Yomb, Y.; Fugon, L.; Nemande, S.; Gueboguo, C.; Larmarange, J.; Trenado, E.; Eboko, F.; Spire, B. // Sexually Transmitted Infections;Apr2010, Vol. 86 Issue 2, p136 

    The article discusses a research study on factors connected with unprotected anal intercourse (UAI) with male partners among men who have sex with men (MSM) group in the city of Douala, Cameroon. Conducted was a survey among MSM men in Douala in 2008 on their sexual activity and practices and...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics