Love is the drug
Related Articles
- Antidepressants. // Journal of Pharmacology & Pharmacotherapeutics;Jul-Sep2012, Vol. 3 Issue 3, p287
The article discusses the risks associated with using antidepressants. It mentions that the drug is found to confer with elevated risk for gastrointestinal and other bleeding complications if it has high affinity for the serotonin transporter. It notes the risk of adverse events in patients with...
- ask ali. // Health (Time Inc. Health);Dec2003, Vol. 17 Issue 10, p86
Answers questions on sexual relationships, pills, holiday gatherings and New Year's resolutions. Factors that could be contributing to low sex drive; Function of antidepressants; Ways to manage time with relatives during holiday.
- Inhibitory Action of Clozapine on Rat Ventral Tegmental Area Dopamine Neurons Following Increased Levels of Endogenous Kynurenic Acid. Schwieler, Lilly; Erhardt, Sophie // Neuropsychopharmacology;Oct2003, Vol. 28 Issue 10, p1770
The mode of action by which the atypical antipsychotic drug clozapine exerts its superior efficacy to ameliorate both positive and negative symptoms is still unknown. In the present in vivo electrophysiological study, we investigate the effects of haloperidol (a typical antipsychotic drug) and...
- WAY-100635 is a potent dopamine D4 receptor agonist. Chemel, Benjamin R.; Roth, Bryan L.; Armbruster, Blaine; Watts, Val J.; Nichols, David E. // Psychopharmacology;Oct2006, Vol. 188 Issue 2, p244
WAY-100635 is a prototypical 5-HT1A receptor antagonist and has been used widely as a pharmacological probe to investigate the distribution and function of 5-HT1A receptors. Results from our studies suggested that WAY-100635 was potently inducing effects unrelated to its 5-HT1A receptor...
- Effects of (-)stepholidine in animal models for schizophrenia. Ellenbroek, Bart A.; Xue-xiang Zhang; Guo-zhang Jin // Acta Pharmacologica Sinica;Sep2006, Vol. 27 Issue 9, p1111
Aim: (-)Stepholidine (SPD) is an active ingredient of the Chinese herb Stephania intermedia, which binds to the dopamine D1 and D2 like receptors. Biochemical, electrophysiological and behavioural experiments have provided strong evidence that SPD is both a D1 and a D2 antagonist, which could...
- Opioids for hedonic experience and dopamine to get ready for it. Barbano, M. Flavia; Cador, Martine // Psychopharmacology;Apr2007, Vol. 191 Issue 3, p497
More than two decades ago, Wise proposed his “anhedonia hypothesis†to explain the role of dopamine in motivated behaviors. The hypothesis posits that dopamine mediates the pleasure experienced by reward obtainment. However, some experimental findings have contested this hypothesis...
- Model-based parametric study of frontostriatal abnormalities in schizophrenia patients. Tanaka, Shoji // BMC Psychiatry;2010, Vol. 10, p17
Background: Several studies have suggested that the activity of the prefrontal cortex (PFC) and the dopamine (DA) release in the striatum has an inverse relationship. One would attribute this relationship primarily to the circuitry comprised of the glutamatergic projection from the PFC to the...
- Amisulpride: a review of its use in the management of schizophrenia. McKeage, Kate; Plosker, Greg L. // CNS Drugs;2004, Vol. 18 Issue 13, p933
Amisulpride (Solian®), a substituted benzamide derivative, is a second-generation antipsychotic that preferentially binds to dopamine D2/D3 receptors in limbic rather than striatal structures. High dosages preferentially antagonise postsynaptic D2/D3 receptors, resulting in reduced dopamine...
- Psychostimulants Induce Low-Frequency Oscillations in the Firing Activity of Dopamine Neurons. Wei-Xing Shi; Chen-Lun Pun; Yan Zhou // Neuropsychopharmacology;Dec2004, Vol. 29 Issue 12, p2160
The reinforcing properties of psychostimulants depend critically on their effects on dopamine (DA) neurons in the ventral tegmental area (VTA). Using in vivo single unit recording in rats and spectral analysis, this study presents evidence for a new, non-DA-mediated effect of psychostimulants on...
