TITLE

Mortality from cancer and chronic respiratory diseases among workers who manufacture carbon electrodes

AUTHOR(S)
Donato, F.; Monarca, S.; Marchionna, G.; Rossi, A.; Cicioni, C.; Chiesa, R.; Colin, D.; Boffetta, P.
PUB. DATE
July 2000
SOURCE
Occupational & Environmental Medicine;Jul2000, Vol. 57 Issue 7, p484
SOURCE TYPE
Academic Journal
DOC. TYPE
journal article
ABSTRACT
Objectives: To investigate the risk of cancer and non-neoplastic respiratory diseases among workers who manufacture carbon electrodes, as this industry entails exposure to mixtures of polycyclic aromatic hydrocarbons. Methods: A historical cohort study was carried out of 1006 male workers employed for at least 1 year between 1945 and 1971 in a carbon (graphite) electrode production plant in central Italy, who were followed up for mortality between 1955 and 1996. The ratio of observed to expected deaths (standardised mortality ratios, SMRs) was computed from both national and (for the period 1964-96) regional age and period specific mortalities. A multivariate Poisson regression analysis was performed to investigate the relative risk (RR) of death according to duration of employment and time since first employment in the factory. Results: A total of 424 workers had died, 538 were still alive, and 44 were lost to follow up. Mortalities from all causes, all cancers, and respiratory tract cancer were in line with the regional figure. An excess was found over the expected deaths from skin cancer including melanoma (SMR 3.16, 95% confidence interval (95% CI) 0.65 to 9.23) and from non-neoplastic respiratory diseases (SMR 1.58, 95% CI 1.16 to 2.11). Poisson regression analysis including age as a covariate showed an increased risk of dying from gastric cancer with increasing duration of employment, and an increase in the RR of dying from lung cancer and from non-neoplastic respiratory diseases with increasing time since first employment, although the linear trend was not significant. Conclusion: This study supports previous findings that working in the carbon electrode manufacturing industry may not increase the risk of dying from respiratory cancer. However, a possible association with non-malignant respiratory diseases cannot be excluded.
ACCESSION #
8716330

 

Related Articles

  • Feeling the Burn. Weinhold, Bob // Environmental Health Perspectives;Oct2007, Vol. 115 Issue 10, pA504 

    A news brief is presented, summarizing the report "Early Childhood Lower Respiratory Illness and Air Pollution" published elsewhere in the issue. The study, conducted on children in the Czech Republic, indicates a link between the incidence of bronchitis in young children and elevated levels of...

  • Occupational exposure to polycyclic aromatic hydrocarbons and lung cancer risk: a multicenter study in Europe. Olsson, Ann C.; Fevotte, Joelle; Fletcher, Tony; Cassidy, Adrian; Mannetje, Andrea't; Zaridze, David; Szeszenia-Dabrowska, Neonila; Rudnai, Peter; Lissowska, Jolanta; Fabianova, Eleonora; Mates, Dana; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Brennan, Paul; Boffetta, Paolo // Occupational & Environmental Medicine;Feb2010, Vol. 67 Issue 2, p98 

    Background Lung cancer incidence in Central and Eastern Europe (CEE) is among the highest in the world, and the role of occupational exposures has not been adequately studied in these countries. Objectives To investigate the contribution of occupational exposure to polycyclic aromatic...

  • Research on airflow models could cut pollution hotspots.  // Professional Engineering;1/14/2004, Vol. 17 Issue 1, p49 

    Presents an update on the project to study the behavior of polluted and hot air released below building heights. Role of The Engineering and Physical Sciences Research Council; Formation of warm air pockets; Cause of respiratory diseases like asthma; Use of sensors to detect naphthalene...

  • Lung Cancer Risk after Exposure to Polycyclic Aromatic Hydrocarbons: A Review and Meta-Analysis. Armstrong, Ben; Hutchison, Emma; Unwin, John; Fletcher, Tony // Environmental Health Perspectives;Jun2004, Vol. 112 Issue 9, p970 

    Typical polycyclic aromatic hydrocarbon mixtures are established lung carcinogens, but the quantitative exposure-response relationship is less dear. To clarify this relationship we conducted a review and meta-analysis of published reports of occupational epidemiologic studies. Thirty-nine...

  • Short-term markers of DNA damage among roofers who work with hot asphalt. Serdar, Berrin; Brindley, Stephen; Dooley, Greg; Volckens, John; Juarez-colunga, Elizabeth; Gan, Ryan // Environmental Health: A Global Access Science Source;10/20/2016, Vol. 15, p1 

    Background: Roofers are at increased risk for various malignancies and their occupational exposures to polycyclic aromatic hydrocarbons (PAHs) have been considered as important risk factors. The overall goal of this project was to investigate the usefulness of phosphorylated histone H2AX...

  • Annibale Carracci The Butcher's Shop c.1583. McKiernan, Mike // Occupational Medicine;Dec2011, Vol. 61 Issue 8, p529 

    No abstract available.

  • Concentrations, particle-size distributions, and indoor/outdoor differences of polycyclic aromatic hydrocarbons (PAHs) in a middle school classroom in Xi'an, China. Xu, Hongmei; Guinot, Benjamin; Niu, Xinyi; Cao, Junji; Ho, Kin; Zhao, Zhuohui; Ho, Steven; Liu, Suixin // Environmental Geochemistry & Health;Oct2015, Vol. 37 Issue 5, p861 

    Polycyclic aromatic hydrocarbons (PAHs) attached to particulate matter can affect respiratory health, especially the health of children, but information on the air quality in schools is generally lacking. This study investigated the PAH concentrations in a naturally ventilated classroom in...

  • Activation of group IVC phospholipase A by polycyclic aromatic hydrocarbons induces apoptosis of human coronary artery endothelial cells. Tithof, Patricia; Richards, Sean; Elgayyar, Mona; Menn, Fu-Minn; Vulava, Vijay; McKay, Larry; Sanseverino, John; Sayler, Gary; Tucker, Dawn; Leslie, Christina; Lu, Kim; Ramos, Kenneth // Archives of Toxicology;Jun2011, Vol. 85 Issue 6, p623 

    Exposure to environmental pollutants, such as polycyclic aromatic hydrocarbons (PAHs) found in coal tar mixtures and tobacco sources, is considered a significant risk factor for the development of heart disease in humans. The goal of this study was to determine the influence of PAHs present at a...

  • A community study of the effect of polycyclic aromatic hydrocarbon metabolites on heart rate variability based on the Framingham risk score. Yingying Feng; Huizhen Sun; Yuanchao Song; Junzhe Bao; Xiji Huang; Jian Ye; Jing Yuan; Weihong Chen; Christiani, David C; Tangchun Wu; Xiaomin Zhang // Occupational & Environmental Medicine;May2014, Vol. 71 Issue 5, p338 

    Objectives To investigate the effects of the urinary metabolite pro les of background exposure to the atmospheric pollutants polycyclic aromatic hydrocarbon (PAH) and Framingham risk score (FRS), which assesses an individual's cardiovascular disease risk, on heart rate variability (HRV). Methods...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics