TITLE

Neural Stem Cells in the Adult Brain: From Benchside to Clinic

AUTHOR(S)
Gonzalez-Perez, Oscar; Garcia-Verdugo, Jose M.; Quinones-Hinojosa, Alfredo; Luquin, Sonia; Gudino-Cabrera, Graciela; Gonzalez-Castaneda, Rocio E.
PUB. DATE
January 2012
SOURCE
Stem Cells International;2012, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
An introduction is presented in which the editor discusses various papers within the issue on topics including neural stem cells and their important role in sustaining cellular homeostasis and brain tissue restoration.
ACCESSION #
87093835

 

Related Articles

  • How inflammation promotes regeneration. Filbin, Marie T. // Nature Neuroscience;Jun2006, Vol. 9 Issue 6, p715 

    The article discusses on the ways on how inflammation promotes regeneration. The idea that inflammation are secreted from macrophages might enhance axonal regeneration. The peripheral conditioning lesion effect can be mimicked either by direct injection of macrophages into the dorsal root...

  • Cross-talk between neural stem cells and immune cells: the key to better brain repair? Kokaia, Zaal; Martino, Gianvito; Schwartz, Michal; Lindvall, Olle // Nature Neuroscience;Aug2012, Vol. 15 Issue 8, p1078 

    Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and activation of endogenous NSPCs hold much promise as potential treatments for diseases in the human CNS. Recent studies have shed new light on the interaction between the NSPCs and cells belonging to the innate and...

  • Comparative aspects of adult neural stem cell activity in vertebrates. Grandel, Heiner; Brand, Michael // Development Genes & Evolution;Mar2013, Vol. 223 Issue 1/2, p131 

    At birth or after hatching from the egg, vertebrate brains still contain neural stem cells which reside in specialized niches. In some cases, these stem cells are deployed for further postnatal development of parts of the brain until the final structure is reached. In other cases, postnatal...

  • Contribution of olfactory neural stem cells to tissue maintenance and regeneration. Leung, Cheuk T.; Coulombe, Pierre A.; Reed, Randall R. // Nature Neuroscience;Jun2007, Vol. 10 Issue 6, p720 

    The olfactory neuroepithelium undergoes continual neurogenesis and, after extensive lesions, fully regenerates to maintain sensory function. The stem cell population underlying this regenerative capacity remains elusive. Here we show that mouse horizontal basal cells (HBCs) function as adult...

  • Overcoming Chondroitin Sulphate Proteoglycan Inhibition of Axon Growth in the Injured Brain: Lessons from Chondroitinase ABC. del Río, J. A.; Soriano, E. // Current Pharmaceutical Design;Aug2007, Vol. 13 Issue 24, p2485 

    The presence of numerous axon-inhibitory molecules limits the capacity of injured neurons in the adult mammalian central nervous system (CNS) to regenerate damaged axons. Among others, chondroitin sulphate proteoglycans (CSPGs) enriched in glycosaminoglycan (GAG) chains, acting intracellularly...

  • Neural Stem Cell Plasticity: Recruitment of Endogenous Populations for Regeneration. Ferretti, Patrizia // Current Neurovascular Research;Jul2004, Vol. 1 Issue 3, p215 

    Lower vertebrates, such as fish and urodele amphibians can regenerate complex body structures including significant portions of their central nervous system by recruiting progenitor cells to repair the damage. Significant ability to regenerate the nervous system is observed also during...

  • Quantitative Assessment of Neurons and Neuroglia with Computer Morphometry. Khudoerkov, R.; Voronkov, D. // Bulletin of Experimental Biology & Medicine;Jan2010, Vol. 149 Issue 1, p100 

    The morphology of neural and glial cells in different cerebral areas and in various experimental models was quantitatively studied by methods of computer morphometry combined with video image analysis systems. The following parameters were obtained: density of neurons and glial cells per 1 mm2,...

  • Cholera Toxin Regulates a Signaling Pathway Critical for the Expansion of Neural Stem Cell Cultures from the Fetal and Adult Rodent Brains. Androutsellis-Theotokis, Andreas; Walbridge, Stuart; Park, Deric M.; Lonser, Russell R.; McKay, Ronald D. G. // PLoS ONE;2010, Vol. 5 Issue 5, p1 

    Background: New mechanisms that regulate neural stem cell (NSC) expansion will contribute to improved assay systems and the emerging regenerative approach that targets endogenous stem cells. Expanding knowledge on the control of stem cell self renewal will also lead to new approaches for...

  • Neural stem cell systems: physiological players or in vitro entities? Conti, Luciano; Cattaneo, Elena // Nature Reviews Neuroscience;Mar2010, Vol. 11 Issue 3, p176 

    Neural stem cells (NSCs) can be experimentally derived or induced from different sources, and the NSC systems generated so far are promising tools for basic research and biomedical applications. However, no direct and thorough comparison of their biological and molecular properties or of their...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics