Surgical synovectomy combined with yttrium 90 in patients with recurrent joint synovitis

Öztemür, Zekeriya; Bulut, Okay; Korkmaz, Murat; Gölge, Umut; Öztürk, Hayati; Tezeren, Gündüz; Günaydın, İlhan
May 2013
Rheumatology International;May2013, Vol. 33 Issue 5, p1321
Academic Journal
Radiation synovectomy (RS) is one of many therapeutic options used for recurrent joint synovitis. Our aim was to analyze the effect of the surgical synovectomy combined with yttrium 90 (Y) in the treatment for recurrent joint synovitis. A surgical combined RS procedure was used on 32 knees of 30 patients. They were divided into two groups. Group 1 consisted of 7 knees of 7 patients (5 women and 2 men) with a mean age of 40.7 years in whom RS was combined with the open synovectomy. Group 2 consisted of 25 knees of 23 patients (21 men and 2 women) with a mean age of 45.5 years in whom RS was combined with the arthroscopic synovectomy. Arthroscopic synovectomy or open surgery biopsy was carried out for all cases who diagnosed of having synovitis. A scintigraphic examination was conducted within 24 h after the RS procedure to investigate the systemic leakage of Y in all patients. The outcome of treatment was assessed based on self-reporting using the visual analogue scale (VAS) of night pain, rest pain, activity pain, effusion, and satisfactory scores. The average follow-up period was 4.15 years. There was a significant difference between before and after treatment in terms of outcome parameters' VAS scores in both groups ( p < 0.05). But there was no statistically significant difference between open and arthroscopic synovectomy groups in terms of outcome parameters ( p > 0.05). Satisfactory outcome was excellent in 3 patients (42.8 %) in group 1 and 8 patients (32 %) in group 2. Surgical synovectomy with combined Y could treat recurrent joint synovitis successfully. There was no statistically significant difference between open and arthroscopic synovectomy techniques combined with RS procedure.


Related Articles

  • Rheumatoid Synovectomy: Does the Surgical Approach Matter? Chalmers, Peter N.; Sherman, Seth L.; Raphael, Bradley S.; Su, Edwin P. // Clinical Orthopaedics & Related Research;Jul2011, Vol. 469 Issue 7, p2062 

    Background: Surgical synovectomy relieves pain in patients with rheumatoid arthritis (RA). The comparative effect of arthroscopic versus open synovectomy on pain reduction, recurrence of synovitis, radiographic progression, and need for subsequent total joint arthroplasty (TJA) is unclear....

  • Development of Y-chitosan as a new agent for radiosynovectomy. Zolghadri, Samaneh; Mirzaei, Alireza; Athari-allaf, Mitra; Yousefnia, Hassan; Jalilian, Amir // Journal of Radioanalytical & Nuclear Chemistry;Oct2015, Vol. 306 Issue 1, p47 

    Radiosynovectomy (RSV) has been applied as an effective treatment to the patients with resistant synovitis for more than 50 years. In this research, Y-chitosan complex was developed as a new agent for use in RSV. Y was obtained from an electrochemical Y/Sr generator. Y-chitosan complex was...

  • Radial Head Excision and Synovectomy in Patients with Hemophilia. Silva, Mauricio; Luck Jr., James V. // Journal of Bone & Joint Surgery, American Volume;Oct2007, Vol. 89-A Issue 10, p2156 

    Background: Chronic hemophilic synovitis of the elbow usually leads to enlargement and erosion of the radial head, resulting in mechanical blockage of forearm rotation, synovial impingement, recurrent hemarthrosis, and pain. The purpose of the present study was to evaluate the intermediate-term...

  • Pigmented villonodular synovitis of the temporomandibular joint: A report of two cases. Church, Christopher A.; Rowe, Mark; Llaurado, Raymund; Liwnicz, Boleslaw H.; Martin, Paul A. // ENT: Ear, Nose & Throat Journal;Sep2003, Vol. 82 Issue 9, p692 

    Pigmented villonodular synovitis is a benign but locally destructive disease that originates in the synovial membranes of the joints. It is a proliferative disorder of unknown etiology, and it is usually monarthric. Approximately 80% of cases involve the knee; the hip, ankle, foot, hand, elbow,...

  • Pigmented villonodular synovitis: a retrospective study of seventy five cases (eighty one joints). Ma, Xiaomei; Shi, Guodong; Xia, Chunyan; Liu, Huimin; He, Jin; Jin, Wentao // International Orthopaedics;Jun2013, Vol. 37 Issue 6, p1165 

    Purpose: Pigmented villonodular synovitis (PVNS) is a relatively rare, benign proliferation lesion of the synovium of large joints, but there is not much information available about the disease's aetiology, clinical history, differential diagnosis, treatment, and long-term effects. We conducted...

  • THE RESULTS OF SYNOVIAL FLUID ANALYSIS AFTER CHEMICAL SYNOVECTOMY.  // Osteoporosis International;Sep2001 Supplement 1, Vol. 12, pS44 

    An abstract of the article "The Results of Synovial Fluid Analysis After Chemical Synovectomy" is presented.

  • Use of yttrium-90 hydroxyapatite radiosynovectomy as a primary modality of treatment in diffuse pigmented villonodular synovitis of the knee joint: A first case report. Kamaleshwaran, Koramadai Karuppusamy; Rajan, David; Krishnan, Boopathi; Gounder, Thirumalaisamy Subbaih; Chakraborty, Sudipta; Kalarickal, Radhakrishnan; Mohanan, Vyshakh; Shinto, Ajit Sugunan // Indian Journal of Nuclear Medicine;Jan-Mar2015, Vol. 30 Issue 1, p47 

    Pigmented villonodular synovitis (PVNS) is a rare, relatively benign, intra-articular lesion characterized by a slowly progressive proliferation of synovial tissue. Knee is the most frequently involved joint. Localized and diffuse forms of synovial involvement were reported. In extensive diffuse...

  • Effectiveness of radiation synovectomy with Yttrium-90 and Samarium-153 particulate hydroxyapatite in rheumatoid arthritis patients with knee synovitis: a controlled, randomized, double-blinded trial. Santos, Marla; Furtado, Rita; Konai, Monique; Castiglioni, Mario; Marchetti, Renata; Silva, Constancia; Natour, Jamil // Clinical Rheumatology;Jan2011, Vol. 30 Issue 1, p77 

    The aim of the present study was to investigate the long-term effectiveness of and tolerance to Yttrium-90 and Samarium-153-particulate hydroxyapatite radiation synovectomy in patients with rheumatoid arthritis (RA) and chronic knee synovitis. Eight-four patients (90 knees) with chronic knee...

  • In-vitro-Untersuchungen zur Dissektion der entzündlichen Synovialis mittels Hochdruck-Flüssigkeitsstrahl (Hydro-Jet-Cutting). Wagner, K.-H.; Tarner, I.H.; Lange, U. // Zeitschrift für Rheumatologie;Oct2012, Vol. 71 Issue 8, p707 

    Surgical synovectomy is a useful therapeutic option for rheumatoid arthritis patients with ongoing active synovitis despite optimal medical therapy. The present experimental study evaluated the novel, minimally invasive surgical technique of hydro-jet cutting in vitro using synovial biopsies....


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics