TITLE

Unilateral Auditory Neuropathy Caused by Cochlear Nerve Deficiency

AUTHOR(S)
Cheng Liu; Xingkuan Bu; Feiyun Wu; Guangqian Xing
PUB. DATE
January 2012
SOURCE
International Journal of Otolaryngology;2012, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective. To explore possible corelationship between the cochlear nerve deficiency (CND) and unilateral auditory neuropathy (AN). Methods. From a database of 85 patients with unilateral profound sensorineural hearing loss, eight who presented with evoked otoacoustic emissions (EOAEs) or cochlear microphonic (CM) in the affected ear were diagnosed with unilateral AN. Audiological and radiological records in eight patients with unilateral AN were retrospectively reviewed. Results. Eight cases were diagnosed as having unilateral AN caused by CND. Seven had type "A" tympanogram with normal EOAE in both ears. The other patient had unilateral type "B" tympanogram and absent OAE but CMrecorded, consistent with middle ear effusion in the affected ear. For all the ears involved in the study, auditory brainstem responses (ABRs) were either absent or responded to the maximum output and the neural responses from the cochlea were not revealed when viewed by means of the oblique sagittal MRI on the internal auditory canal. Conclusion. Cochlear nerve deficiency can be seen by electrophysiological evidence and may be a significant cause of unilateral AN. Inclined sagittal MRI of the internal auditory canal is recommended for the diagnosis of this disorder.
ACCESSION #
87021673

 

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