TITLE

Generalized estimating equations: A hybrid approach for mean parameters in multivariate regression models

AUTHOR(S)
Lange, Christoph; Whittaker, John C.; MacGregor, Alex J.
PUB. DATE
August 2002
SOURCE
Statistical Modelling: An International Journal;2002, Vol. 2 Issue 3, p163
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We propose an extension of the generalized estimating equation approach to multivariate regression models (Liang and Zeger, 1986) which allows the estimation of dispersion and association parameters in the covariance matrix partly using estimating equations as in Prentice and Zhao (1991), and partly by the direct use of consistent estimators. The advantages of this hybrid approach over that of Prentice and Zhao (1991) are a reduction in the number of fourth moment assumptions that must be made, and the consequent reduction in numerical complexity. We show that the type of estimation used for covariance parameters does not affect the asymptotic efficiency of the mean parameter estimates. The advantages of the hybrid model are illustrated by a simulation study. This work was motivated by problems in statistical genetics, and we illustrate our approach using a twin study examining association between the osteocalcin receptor and various osteoporisis-related traits.
ACCESSION #
8687638

 

Related Articles

  • Statistical methods for the analysis and presentation of the results of bone marrow transplants. Part 2: Regression modeling. Klein, J P; Rizzo, J D; Zhang, M-J; Keiding, N // Bone Marrow Transplantation;12/1/2001, Vol. 28 Issue 11, p1001 

    In this paper, we address methods of multivariate regression. We discuss the value of regression compared to matched pairs analysis, methods of coding variables, basic concepts of the Cox model and interpretation of results of the Cox model. We present methods of handling variables whose effect...

  • Misconceptions About Nested Studies, Matched Analysis, Significancy, Power, Normality and Multivariate Regression Analysis. Kabir, Ali // Hepatitis Monthly;Feb2013, Vol. 13 Issue 2, p1 

    A letter to the editor is presented in response to the article related with thyroid dysfunction.

  • POLYNOMIAL REGRESSION: A LINEAR VECTOR SPACE PERSPECTIVE. Baderian, Armen; Javadi, Mohammad // Mathematics & Computer Education;Spring2014, Vol. 48 Issue 2, p164 

    The article describes a method of finding a closest fitting curve to a set of data points using linear regression method.

  • Assemblages of peracarid crustaceans in subtidal sediments from the Ría de Aldán (Galicia, NW Spain). Antía Lourido; Juan Moreira; Jesús Troncoso // Helgoland Marine Research;Dec2008, Vol. 62 Issue 4, p289 

    Abstract  Peracarid crustaceans inhabit many marine benthic habitats and are good indicators of environmental conditions. There is, however, a lack of information about diversity and distribution of peracarid crustaceans on the shallow subtidal sediments of the Galician rias. In...

  • Improper Reporting of Multivariable Logistic Regression. Kumar, Rajeev // Indian Journal of Psychological Medicine;Jan-Mar2014, Vol. 36 Issue 1, p102 

    A letter to the editor is presented in response to the article regarding improper reporting of multivariable logistic regression (MLR).

  • Difficulties Detecting Fraud? The Use of Benford's Law on Regression Tables. Bauer, Johannes; Gross, Jochen // Jahrbucher fur Nationalokonomie & Statistik;2011, Vol. 231 Issue 5/6, p733 

    The occurrence of scientific fraud damages the credibility of science. An instrument to discover deceit was proposed with Benford's law, a distribution which describes the probability of significant digits in many empirical observations. If Benford-distributed digits are expected and empirical...

  • A group bridge approach for variable selection. Jian Huang; Shuange Ma; Huiliang Xie; Cun-Hui Zhang // Biometrika;Jun2009, Vol. 96 Issue 2, p339 

    In multiple regression problems when covariates can be naturally grouped, it is important to carry out feature selection at the group and within-group individual variable levels simultaneously. The existing methods, including the lasso and group lasso, are designed for either variable selection...

  • Retirement intentions of dentists in New South Wales, Australia. Schofield, Deborah; Fletcher, Susan; Page, Sue; Callander, Emily // Human Resources for Health;2010, Vol. 8, p9 

    Background: The Australian dental workforce is ageing and current shortages have been predicted to worsen with the retirement of the growing contingent of older dentists. However, these predictions have been based on retirement trends of previous generations and little is known about the...

  • Set Relations in Social Research: Evaluating Their Consistency and Coverage. Charles C. Ragin // Political Analysis;Jul2006, Vol. 14 Issue 3, p291 

    Because of its inherently asymmetric nature, set-theoretic analysis offers many interesting contrasts with analysis based on correlations. Until recently, however, social scientists have been slow to embrace set-theoretic approaches. The perception was that this type of analysis is restricted to...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics