A Rare Presentation of a Rare Disease: Pulmonary Lymphomatoid Granulomatosis

Mohyuddin, Ghulam Rehman; Sultan, Fatima; Khaleeq, Ghulam
January 2012
Case Reports in Pulmonology;2012, p1
Academic Journal
A 70-year-old female presented with a 4-week history of dry cough and wheezing. Chest radiograph showed a 10.5 cm masslike density in the anterior mediastinum which had not been previously visualized. Computed tomography scan (CT) of the chest showed a right hilar mass encasing and narrowing right upper lobe bronchus and right mainstem bronchus and secondary atelectatic changes. Biopsy was consistent with a diagnosis of lymphomatoid granulomatosis Grade 3. She responded well clinically and radiologically to therapy. Lymphomatoid granulomatosis is a rare EBV-associated disorder which is considered a lymphoproliferative disease. The most common radiographic feature is multiple lung nodules. An isolated hilar mass is an exceptionally rare presentation of this rare disease.


Related Articles

  • Diagnosing breathlessness. Morris, David // Independent Nurse;9/21/2009, p20 

    The article presents a diagnostic case of a 54-year-old man named Brian who initially reported a three-week history of shortness of breath, dry cough and nocturnal wheezing. Brian was prescribed doxycycline and prednisolone, not withstanding the possibility that might have chronic obstructive...

  • Asthma or Not? The Value of Flow Volume Loops in Evaluating Airflow Obstruction. Lin, Debby A.; Arm, Jonathan P. // Allergy & Asthma Proceedings;Mar/Apr2003, Vol. 24 Issue 2, p107 

    Large airway obstruction can present with symptoms typically associated with asthma, including cough, dyspnea, or wheezing. Obstruction of the large airways should he considered in the differential diagnosis of patients with difficult to manage asthma, particularly those with known risk factors...

  • Posterior mediastinal Castelman's disease presented as hypervascular lipomatous tumor. Michaelides, M.; Nikolaidou, A.; Konstantinou, D.; Balis, G. C.; Tsitouridis, I. // Hippokratia;Oct2011, Vol. 15 Issue 4, p361 

    Castelman's disease (CD) is a rare lymphoproliferative disorder most often found in the chest. Herein we describe the imaging findings of a histologically proven case of CD involving the posterior mediastinum in a 41-year-old asymptomatic man presented as a well-defined hypervascular lipomatous...

  • Find the missing millions who have declining lung function. Duffin, Christian // Primary Health Care;Nov2011, Vol. 21 Issue 9, p4 

    The article reports on the urging of nurses to uncover chronic obstructive pulmonary disease (COPD) in people being administered winter flu vaccination in Great Britain in 2011.

  • Th1/Th2 cytokine pattern in bronchoalveolar lavage fluid and induced sputum in pulmonary sarcoidosis. Tsiligianni, Ioanna; Antoniou, Katerina M.; Kyriakou, Despina; Tzanakis, Nikolaos; Chrysofakis, George; Siafakas, Nikolaos M.; Bouros, Demosthenes // BMC Pulmonary Medicine;2005, Vol. 5, p8 

    Background: Sarcoidosis is thought to be a T-helper type 1 cytokine (Th2 cytokine) mediated disorder. Induced sputum (IS) has been proposed as a useful non-invasive method, mainly for the assessment of the airway diseases. The aim of this study was to explore induced sputum (IS) CD4+Th1...

  • Apoptosis resistant bronchoalveolar lavage (BAL) Fluid lymphocytes in sarcoidosis. Stridh, H.; Planck, A.; Gigliotti, D.; Eklund, A.; Grunewald, J. // Thorax;Oct2002, Vol. 57 Issue 10, p897 

    Background: Sarcoidosis is a chronic granulomatous lung disease of unknown origin. The accumulation of activated I cells at sites of inflammation represents an early stage in granuloma formation. Since mechanisms governing the normal resolution of inflammatory processes are poorly understood,...

  • Answer.  // Thorax;Jul2008, Vol. 63 Issue 7, p848 

    The article provides an answer to a question on the diagnosis of a patchy consolidation at the apical segment of the left lower lobe associated with productive cough.

  • How to investigate a patient with suspected interstitial lung disease. Dempsey, Owen J.; Kerr, Keith M.; Remmen, Hardy; Denison, Alan R. // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;6/12/2010, Vol. 340 Issue 7759, p1294 

    Persistent crackles on chest auscultation may be due to interstitial lung disease and should prompt a detailed history and some first line tests including a chest radiograph Some commonly prescribed drugs, environmental dusts, smoking, and underlying connective tissue diseases can cause...

  • Identifying the causes of persistent cough. Perry, Margaret // Practice Nurse;2/9/2007, Vol. 33 Issue 3, p43 

    The article offers clinical information on persistent cough. In diagnosing persistent cough, patient history should be comprehensive, including details of any other health problems that the patient may have, past medical history, family history, smoking, alcohol and employment history. Some...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics