TITLE

Sensitivity to Rocuronium-Induced Neuromuscular Block and Reversibility with Sugammadex in a Patient with Myotonic Dystrophy

AUTHOR(S)
Kashiwai, Akihiro; Suzuki, Takahiro; Ogawa, Setsuro
PUB. DATE
January 2012
SOURCE
Case Reports in Anesthesiology;2012, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We report a patient with myotonic dystrophy who showed prolonged rocuronium-induced neuromuscular blockade, although with a fast recovery with sugammadex. During general anesthesia with propofol and remifentanil, the times to spontaneous recovery of the first twitch (T1) of train of four to 10% of control values after an intubating dose of rocuronium 1mg/kg and an additional dose of 0.2 mg/kg were 112 min and 62 min, respectively. Despite the high sensitivity to rocuronium, sugammadex 2mg/kg administered at a T1 of 10% safely and effectively antagonized rocuronium-induced neuromuscular block in 90 s.
ACCESSION #
86827065

 

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