TITLE

CK2-dependent phosphorylation of the E2 ubiquitin conjugating enzyme UBC3B induces its interaction with β-TrCP and enhances β-catenin degradation

AUTHOR(S)
Semplici, Francesca; Meggio, Flavio; Pinna, Lorenzo A.; Oliviero, Salvatore
PUB. DATE
June 2002
SOURCE
Oncogene;6/6/2002, Vol. 21 Issue 25, p3978
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Provides information on a study which focused on the identification by yeast interaction trap of a CK2 interacting protein, which is highly homologous to the E2 ubiquitin conjugating enzyme. Characteristics of protein kinase CK2; Aspects that enhance the degradation of β-catenin; Factor that triggers cell cycle progression.
ACCESSION #
8660462

 

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