TITLE

Characterization and In-vitro Properties of Composite Materials

AUTHOR(S)
Mohamed, K. R.; Orban, H.; Mohamed, A. M.
PUB. DATE
March 2013
SOURCE
Interceram: International Ceramic Review;Mar2013, Vol. 62 Issue 1, p40
SOURCE TYPE
Trade Publication
DOC. TYPE
Article
ABSTRACT
The present work is concerned with the effect of chitosan polymer concentration on the properties of hydroxyapatite/chitosan--gelatin composite materials. The prepared composites were characterized by Fourier transform infrared spectroscopy, thermo-gravimetric analysis, and scanning electron microscopy. Also, in vitro degradation and swelling tests were performed. The results showed that the increase of chitosan content in the composites in the presence of citric acid improved its compressive strength. The swelling of the composites increased with the increase of chitosan proving high water affinity. The degradation of the composites was directly proportional to the chitosan content but it reduced in the presence of citric acid due to an increase of the binding strength. In vitro data proved that the high content of chitosan with a fixed content of gelatin and citric acid in the composites enhanced the formation of carbonated hydroxyapatite on their surfaces; therefore, these biocomposites materials are promising for bone grafting and bio-applications.
ACCESSION #
86442209

 

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