TITLE

Sulfide as a signaling molecule in autophagy

AUTHOR(S)
Gotor, Cecilia; García, Irene; Crespo, José L.; Romero, Luis C.
PUB. DATE
April 2013
SOURCE
Autophagy;Apr2013, Vol. 9 Issue 4, p609
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
86440363

 

Related Articles

  • Small-molecule inhibitors: bULKing up mTOR inhibition. Goodwin, Jonathan M; Murphy, Leon O // Nature Chemical Biology;Oct2015, Vol. 11 Issue 10, p758 

    The article reports on a study which describes the potential cancer treatment with a new small-molecule inhibitor of the autophagy mTORC1 complex. The researchers have demonstrated an autophagy in genetic metabolic demands to maintain cellular homeostasis and promote survival. The study expands...

  • Effects of hydrogen sulfide on myocardial fibrosis and PI3K/AKT1-regulated autophagy in diabetic rats. TING XIAO; JIAN LUO; ZHIXIONG WU; FANG LI; OU ZENG; JUN YANG // Molecular Medicine Reports;2016, Vol. 13 Issue 2, p1765 

    Myocardial fibrosis is the predominant pathological characteristic of diabetic myocardial damage. Previous studies have indicated that hydrogen sulfide (H2S) has beneficial effects in the treatment of various cardiovascular diseases. However, there is little research investigating the effect of...

  • Cysteine and Cysteine-Related Signaling Pathways in Arabidopsis thaliana. Romero, Luis C.; Aroca, M. Ángeles; Laureano-Marín, Ana M.; Moreno, Inmaculada; García, Irene; Gotor, Cecilia // Molecular Plant (Oxford University Press / USA);Feb2014, Vol. 7 Issue 2, p264 

    Cysteine occupies a central position in plant metabolism. In this review, we describe the current knowledge concerning the importance of cysteine and its derivative molecules in Arabidopsis thaliana. We unravel the role of these compounds in both the signaling and control of different plant...

  • Hydrogen Sulfide Ameliorates Ischemia/Reperfusion-Induced Hepatitis by Inhibiting Apoptosis and Autophagy Pathways. Ping Cheng; Fan Wang; Kan Chen; Miao Shen; Weiqi Dai; Ling Xu; Yan Zhang; Chengfen Wang; Jingjing Li; Jing Yang; Rong Zhu; Huawei Zhang; Yuanyuan Zheng; Jie Lu; Yingqun Zhou; Chuanyong Guo // Mediators of Inflammation;2014, Vol. 2014, p1 

    Background. Hepatic ischemia/reperfusion (I/R) injury is an important clinical problem, and its consequences can seriously threaten human health. Apoptosis and autophagy have been shown to contribute to cell death in hepatic I/R injury. Hydrogen sulfide (H2S) is the third most common...

  • Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes. Sciarretta, Sebastiano; Yee, Derek; Ammann, Paul; Nagarajan, Narayani; Volpe, Massimo; Frati, Giacomo; Sadoshima, Junichi // Clinical Science;Apr2015, Vol. 128 Issue 7, p387 

    In the past several years, it has been demonstrated that the reactive oxygen species (ROS) may act as intracellular signalling molecules to activate or inhibit specific signalling pathways and regulate physiological cellular functions. It is now well-established that ROS regulate autophagy, an...

  • Autophagy signal transduction by ATG proteins: from hierarchies to networks. Wesselborg, Sebastian; Stork, Björn // Cellular & Molecular Life Sciences;Dec2015, Vol. 72 Issue 24, p4721 

    Autophagy represents an intracellular degradation process which is involved in both cellular homeostasis and disease settings. In the last two decades, the molecular machinery governing this process has been characterized in detail. To date, several key factors regulating this intracellular...

  • Rab12 regulates mTORC1 activity and autophagy through controlling the degradation of amino-acid transporter PAT4. Matsui, Takahide; Fukuda, Mitsunori // EMBO Reports;May2013, Vol. 14 Issue 5, p450 

    Autophagy is an evolutionarily conserved catabolic mechanism that targets intracellular molecules and damaged organelles to lysosomes. Autophagy is achieved by a series of membrane trafficking events, but their regulatory mechanisms are poorly understood. Here, we report small GTPase Rab12 as a...

  • Signaling in the plant cytosol: cysteine or sulfide? Gotor, Cecilia; Laureano-Marín, Ana; Moreno, Inmaculada; Aroca, Ángeles; García, Irene; Romero, Luis // Amino Acids;Oct2015, Vol. 47 Issue 10, p2155 

    Cysteine (Cys) is the first organic compound containing reduced sulfur that is synthesized in the last stage of plant photosynthetic assimilation of sulfate. It is a very important metabolite not only because it is crucial for the structure, function and regulation of proteins but also because...

  • Pan-Bcl-2 inhibitor Obatoclax is a potent late stage autophagy inhibitor in colorectal cancer cells independent of canonical autophagy signaling. Koehler, Bruno Christian; Jassowicz, Adam; Scherr, Anna-Lena; Lorenz, Stephan; Radhakrishnan, Praveen; Kautz, Nicole; Elssner, Christin; Weiss, Johanna; Jaeger, Dirk; Schneider, Martin; Schulze-Bergkamen, Henning // BMC Cancer;11/19/2015, Vol. 15, p1 

    Background: Colorectal cancer is the third most common malignancy in humans and novel therapeutic approaches are urgently needed. Autophagy is an evolutionarily highly conserved cellular process by which cells collect unnecessary organelles or misfolded proteins and subsequently...

  • Role of autophagy in neurodegenerative diseases. Sarkar, Sovan // Current Science (00113891);8/25/2011, Vol. 101 Issue 4, p514 

    The growing range of implications of autophagy in a myriad of human physiological and pathological conditions has witnessed an exponential increase in the number of studies published over the last decade. The role of autophagy to function predominantly as a cellular survival mechanism has been...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics