TITLE

Oxidative stress and cardiovascular health: therapeutic potential of polyphenols1

AUTHOR(S)
Khurana, Sandhya; Piche, Matthew; Hollingsworth, Amanda; Venkataraman, Krishnan; Tai, T.C.
PUB. DATE
March 2013
SOURCE
Canadian Journal of Physiology & Pharmacology;Mar2013, Vol. 91 Issue 3, p198
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Reactive oxygen species (ROS) are important in normal cellular function and physiology. However, oxidative stress resulting from an accumulation of ROS has a detrimental impact on cellular function, and ROS has been implicated in the pathogenesis of a number of diseases, including cardiovascular diseases. This review provides a summary of the impact of ROS on cardiovascular health and diseases, highlighting the therapeutic use of antioxidants. In addition, this review summarizes the health benefits of polyphenols, and the recent progress on understanding the cellular and physiological actions by which polyphenols may impart their beneficial properties on cardiovascular health.
ACCESSION #
86421652

 

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