TITLE

FREE RADICAL SCAVENGING AND ANTIOXIDANT POTENTIAL OF THESPESIA POPULNEA (L.) FLOWER EXTRACT

AUTHOR(S)
PATIL, P.S.; VENKATNARAYANAN, R.D.; ARGADE, P.D.; SHINDE, P.R.
PUB. DATE
April 2012
SOURCE
International Journal of Pharmacy & Pharmaceutical Sciences;Apr2012 Supplement 3, Vol. 4, p561
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: Antioxidants are act as scavengers and play the housekeeper's role by mopping up free radicals before they possibly will get a chance to create havoc in a body. Thus they may well be defined as the substances that are capable of quenching or stabilizing free radicals. Thespesia populnea widely distributed throughout the India mostly found in Coast forests and evergreen forest of Western Ghats, largely grown as a roadside tree in tropical regions. Objective: To evaluate the antioxidant potential of flower of Thespesia populnea; yet unreported. Material and Method: Antioxidant potential of methanolic extract of flower (TPF) was evaluated by in- vitro antioxidant studies like free radical scavenging activity by DPPH method, nitric oxide method, anti- lipid peroxidation study, and reducing power assay and expressed as % scavenging and IC50. Ascorbic acid was served as standard for the study. Result: The phytochemical screening of the extract mainly revealed the presence of terpenoids and flavonoids mainly; whereas the HPTLC profile of extract confirmed the presence of β- sitosterol in the extract. The extract showed the significant antioxidant activity as compared to control; but comparatively less than the ascorbic acid. The antioxidant potential was increased in dose dependant manner. Conclusion: From the present study it can be conclude that TPF exhibits better antioxidant activity due to prominent presence of vital bioactive constituents.
ACCESSION #
86242868

 

Related Articles

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics