Suizidprophylaktische Wirkung von Lithium

Lewitzka, U.; Bauer, M.; Felber, W.; Müller-Oerlinghausen, B.
March 2013
Der Nervenarzt;Mar2013, Vol. 84 Issue 3, p294
Academic Journal
Treatment of patients with suicidal behaviour is one of the most challenging tasks for health care professionals. Due to the high mortality, morbidity and costs related to suicide, the development of treatment and preventive strategies for suicidal behaviour have been a focus of psychiatric research. For lithium, one of the oldest pharmacological agents used in psychiatry, anti-suicidal effects have been found since the early 90s in many international studies. Despite this unambiguous evidence and corresponding recommendations in national and international guidelines for the acute and maintenance therapy of affective disorders, the use of lithium is still underrepresented. The following article provides a review of studies investigating the anti-suicidal effects of lithium in affective disorders. Clinical implications for the treatment of affective disorders are discussed.


Related Articles

  • The International Consortium on Lithium Genetics (ConLiGen): An Initiative by the NIMH and IGSLI to Study the Genetic Basis of Response to Lithium Treatment. Schulze, Thomas G.; Alda, Martin; Adli, Mazda; Akula, Nirmala; Ardau, Raffaella; Bui, Elise T.; Chillotti, Caterina; Cichon, Sven; Czerski, Piotr; Del Zompo, Maria; Detera-Wadleigh, Sevilla D.; Grof, Paul; Gruber, Oliver; Hashimoto, Ryota; Hauser, Joanna; Hoban, Rebecca; Iwata, Nakao; Kassem, Layla; Kato, Tadafumi; Kittel-Schneider, Sarah // Neuropsychobiology;2010, Vol. 62 Issue 1, p72 

    For more than half a decade, lithium has been successfully used to treat bipolar disorder. Worldwide, it is considered the first-line mood stabilizer. Apart from its proven antimanic and prophylactic effects, considerable evidence also suggests an antisuicidal effect in affective disorders....

  • The Suicidal Client/Parishioner: A Guide for Clergy, Pastoral Counselors, and Psychologists Who Advise Them. Schoener, Gary R. // Minnesota Psychologist;Mar/Apr2011, Vol. 60 Issue 2, p15 

    The article discusses guidelines for clergy, pastoral counselors and psychologists in dealing with suicidal parishioners and clients in Minnesota. These involve competence of risk assessment, decision of breaching confidentiality to avoid imminent suicide and assistance of affected parties...

  • ENDING YOUR LIFE IS NOT THE ANSWER TO YOUR SITUATION. Popovich, Stan // Oklahoma Woman;Dec2011/Jan2012, p6 

    The article offers pieces of advice to help individuals understand why suicide is not an option to their problems. Several reasons being discussed include the notion that things change over time as well as no one can predict the future and to focus on the facts of the situation and not on one's...

  • Lithium enhances alveolar bone formation during orthodontic retention in rats. Pan, J.; He, S.; Yin, X.; Li, Y.; Zhou, C.; Zou, S. // Orthodontics & Craniofacial Research;Aug2017, Vol. 20 Issue 3, p146 

    Objective: To investigate the effect of lithium on alveolar bone formation during orthodontic retention in rats.Materials and Methods: After 2 weeks of orthodontic tooth movement (OTM), 42 8-week-old male Wistar rats were randomly divided into two orthodontic...

  • Chronic Stress May Not Be a Factor in the Behavioral Response to Chronic Lithium in ICR Mice. Shemesh, Gil; Kara, Nirit; Einat, Haim // Pharmacology;Nov2018, Vol. 102 Issue 5/6, p281 

    Background: Lithium (Li) is the prototypic mood-stabilizing drug, but the individual response to Li is highly heterogeneous. Some evidence suggest interactions between Li and stress, and it is possible to hypothesize that lithium's effects are modified by stress conditions. The current study...

  • A Small but Potentially Significant Role in Suicide Prevention. Diiulio, R. // Imaging Economics;Jan2011, Vol. 24 Issue 1, p18 

    The article focuses on the warning given by the Joint Commission Sentinel Event Alert to the medical community on the occurrence of suicide, in which the warning was intended for medical personnel in the emergency and radiology departments.

  • Lithium: proving its mettle for 50 years. Friedrich, M.J. // JAMA: Journal of the American Medical Association;6/23/99, Vol. 281 Issue 24, p2271 

    Discusses 50 years of lithium's medical usefulness. Claims for lithium's healing powers in the late 1800s and early 1900s; Mention of paper published by Australian psychiatrist John Cade in 1949; Details about a study by Dr. Paul Grof et al of patients shown to be excellent responders to...

  • Review: Long-term lithium treatment lowers suicide risk in major affective disorder. Burgess, Sally // ACP Journal Club;Mar/Apr2002, Vol. 136 Issue 2, p63 

    Focuses on a study which investigated the association of long-term lithium treatment with lower-suicide risk in patients with a major affective disorder. Methodology of the study; Results; Comments on the study.

  • Lithium Reduces Pathological Aggression and Suicidality: A Mini-Review. Müller-Oerlinghausen, Bruno; Lewitzka, Ute // Neuropsychobiology;2010, Vol. 62 Issue 1, p43 

    From a practical point of view, the well-proven antisuicidal and anti-aggressive effects of lithium are of utmost importance for a rational, safe and economical treatment of patients with affective disorders. Regular lithium long-term treatment reduces the otherwise 2- to 3-fold increased...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics