Science & Super Mice

Rowley, Brian
July 2002
Joe Weider's Muscle & Fitness;Jul2002, Vol. 63 Issue 7, p80
Examines the impact of the transgenic growth factor on bodybuilding science. Details of the work done on genetically engineered strain of super mice; Percentage of mice that experienced increase in muscle mass; Link between stimulus and growth.


Related Articles

  • Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice. Wang, Timothy C.; Cardiff, Robert D. // Nature;6/23/1994, Vol. 369 Issue 6482, p669 

    Examines the consequences of overexpression of cyclin D1 in transgenic mice. Central role for cyclins in growth control; Abnormal mammary cell proliferation; Development of mammary adenocarcinomas; Oncogenic role in breast cancer.

  • Million-dollar mice.  // New Internationalist;Dec2000, Issue 330, p7 

    Reports on the attention attracted the alleged most expensive variety of a transgenic mouse, the TG2576 or the Hsaio Mouse. Alteration of the mouse's gene to contract Alzheimer's disease; Cost benefits derived from the transgenic mouse in terms of research costs.

  • Spare the mice. Walker, Matt // New Scientist;07/26/97, Vol. 155 Issue 2092, p5 

    Cites toxicologist Michael Festing's call for use of inbred strains of mice in toxicology experiments. Data noise brought by using outbred strains; Need to reduce the number of rodents used in toxicity.

  • Might mammalian mitochondria merge? Turnbull, Douglass M.; Lightowlers, Robert N. // Nature Medicine;Aug2001, Vol. 7 Issue 8, p895 

    Reports on the development of a transgenic mouse model carrying pathogenic mitochondria DNA. Scarcity of evidence for the dynamic nature of mammalian mitochondria; Background on mitochondrial DNA diseases as a group of genetic disorders.

  • Hippocampal immunostaining of CCK-GAD1 transgenic mice. Schmidt, M J; Horvath, S; Ebert, P; Norris, J L; Seeley, E H; Brown, J; Gellert, L; Everheart, M; Garbett, K A; Grice, T W; Caprioli, R M; Mirnics, K // Molecular Psychiatry;May2014, Vol. 19 Issue 5, p529 

    An image is presented depicting the Hippocampal CA3 region triple-immunostaining in transgenic mice.

  • Reduced troponin I phosphorylation and increased Ca2+-dependent ATP-consumption in triton X-skinned fiber preparations from Gαq overexpressor mice. C. Pott; L. Willkomm; S. Grafweg; B. Bölck; G. Dorn; R. Schwinger; K. Brixius // Molecular & Cellular Biochemistry;Jul2008, Vol. 314 Issue 1/2, p133 

    Abstract  Overexpression of the Gαq-protein has been shown to result in hypertrophic and dilated cardiomyopathy. This study investigated Ca2+ sensitivity of tension and myosin-ATPase activity in skinned fiber preparations of male and female wildtype (WT; n = 12) and transgenic...

  • Protective action of tetramethylpyrazine phosphate against dilated cardiomyopathy in cTnTR141W transgenic mice. Hai-ping ZHAO; Dan LÜ; Wei ZHANG; Li ZHANG; Shu-mei WANG; Chun-mei MA; Chuan QIN; Lian-feng ZHANG // Acta Pharmacologica Sinica;Mar2010, Vol. 31 Issue 3, p281 

    AbstractAim:Dilated cardiomyopathy (DCM) is the most common cause of heart failure, and pharmacological intervention is not currently available. Here we investigate the effect of tetramethylpyrazine phosphate (TMPP) on the progression of DCM in the cTnTR141W transgenic mouse model.Methods:The...

  • Expanding our Understanding of Polyglutamine Disease Through Transgenic Mice. Davidson, Jennifer D.; Orr, Harry T. // Current Genomics;Mar2001, Vol. 2 Issue 1, p27 

    Knowing the mutational basis of a disease does not always explain the mechanism of pathogenesis, particularly when little is known about the disease-associated proteins themselves. This is very likely to be an ever-growing problem in the genomics era. The polyglutamine (polyQ) repeat disorders...

  • Mouse Cellular Cementum is Highly Dependent on Growth Hormone Status. Smid, J. R.; Rowland, J. E.; Young, W. G.; Daley, T. J.; Coschigano, K. T.; Kopchick, J. J.; Waters, M. J. // Journal of Dental Research;Jan2004, Vol. 83 Issue 1, p35 

    Cementum is known to be growth-hormone (GH) -responsive, but to what extent is unclear. This study examines the effects of extremes of GH status on cementogenesis in three lines of genetically modified mice; GH excess (giant), GH antagonist excess (dwarf), and GH receptor-deleted (GHR-KO)...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics