Efficacy of the local endometrial injury in patients who had previous failed IVF-ICSI outcome

Mustafa Kara; Turgut Aydin; Nurettin Turktekin; S., Karacavus
November 2012
Iranian Journal of Reproductive Medicine;Nov2012, Vol. 10 Issue 6, p567
Academic Journal
Background: The latest studies reported that local endometrial injury is a useful method to improve the success of IVF-ICSI outcome. Objective: To assess whether local endometrial injury occurred by Pipelle in the spontaneous cycle could improve implantation rate, cleavage rate, and pregnancy outcome in the subsequent IVF-ICS1 cycle in patients who had recurrent IVF failure. Materials and Methods: An endometrial biopsy was performed on day 21st in 41 patients as intervention group in this retrospective cross-sectional study. The control group contained 42 women. Results: Implantation rate was 22.5% and 10.5% in intervention and control group, respectively and this difference was found to be statistically significant (p=001). Pregnancy rate was 43.9% in the intervention group and this parameter was significantly lower in control group (21.4%) (p=0.03). Conclusion: Local endometrial injury in the nontransfer cycle increases the implantation rate and pregnancy rate in the subsequent IVF-ICSI cycle in patients who had previous failed IVF-ICSI outcome.


Related Articles

  • Pregnancy outcome in severe OHSS patients following ascitic/plerural fluid drainage. Haas, Jigal; Yinon, Yoav; Meridor, Katya; Orvieto, Raoul // Journal of Ovarian Research;2014, Vol. 7 Issue 1, p1 

    Background Various inflammatory cytokines have been implicated in the pathophysiology of severe ovarian hyperstimulation syndrome, as well as, various pregnancy complications, including preterm labor, pregnancy induced hypertension/preeclampsia and intra-uterine growth restriction. We aim to...

  • Ovarian Stimulation Changes the Intrauterine Milieu.  // Fertility Weekly;11/22/2010, p10 

    The article discusses a study which examines the effect of ovarian stimulation on the intrauterine environment performed before in vitro fertilization (IVF). Women who have regular menstrual cycles and will undergo IVF participated in the study. Gonadotropin releasing hormone (GnRH) antagonist...

  • FOLLICULAR FLUID SELECTIVE HORMONES AND CYTOKINES CONCENTRATION AND RELATIONSHIP WITH EMBRYO IMPLANTATION IN WOMEN UNDERGOING INTRACYTOPLASMIC SPERM INJECTION METHOD IN MOTAHHARI HOSPITAL, URMIA. Ilkhanizadeh, B.; Moghaddam, A. Nahali; Hajshfiha, M.; Deldar, Y.; Asadi, N.; Kiarang, N. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Oct2010 S3 Supplemen, Vol. 20, pS64 

    Objective: Concentrations of certain substances in follicular fluid (FF) may related to fertilization outcome. The study aim was to identify FF markers with which to predict embryo implantation potential. Materials and Methods: Concentrations of selected hormones cytokines and growth factors in...

  • The effect of smoking on oocyte quality and hormonal parameters of patients undergoing in vitro... Weigert, Monika; Hofstetter, Gerda // Journal of Assisted Reproduction & Genetics;Jul99, Vol. 16 Issue 6, p287 

    Investigates the physiological effect of smoking on oocyte quality and hormonal parameters of patients undergoing in vitro fertilization-embryo transfer. Oocyte count; Embryo score; Basal hormone values; Number of fertilized and transferred oocyte suitable for cryopreservation; Higher basal...

  • Ultrasound and the receptivity of the endometrium. Killick, Stephen R. // Reproductive BioMedicine Online (Reproductive Healthcare Limited;Jul2007, Vol. 15 Issue 1, p63 

    Ultrasound imaging can be used to assess the endometrium in a number of ways. In particular, time-lapse video recordings can show that the lining of the uterus undergoes rhythmical contractions that vary in strength and intensity throughout the ovarian cycle. These contractions appear to assist...

  • The blastocyst. Hardarson, Thorir; Van Landuyt, Lisbet; Jones, Gayle // Human Reproduction;Aug2012 Supplement 1, Vol. 27 Issue suppl_1, pi72 

    No abstract available.

  • From the Editor's desk. Patil, Madhuri // Journal of Human Reproductive Sciences;Jul-Sep2015, Vol. 8 Issue 3, p119 

    No abstract available.

  • Vitamin D deficiency and pregnancy rates in women undergoing single embryo, blastocyst stage, transfer (SET) for IVF/ICSI. Polyzos, Nikolaos P.; Anckaert, Ellen; Guzman, Luis; Schiettecatte, Johan; Van Landuyt, Lisbet; Camus, Michel; Smitz, Johan; Tournaye, Herman // Human Reproduction;Sep2014, Vol. 29 Issue 9, p2032 

    STUDY QUESTION What is the influence of vitamin D deficiency on pregnancy rates among women undergoing IVF/ICSI and Day 5 (blastocyst stage) single embryo transfer (SET)? SUMMARY ANSWER Vitamin D deficiency results in significantly lower pregnancy rates in women undergoing single blastocyst...

  • Placental and Fetal Findings in Intrauterine Candida lusitaniae Infection Following in Vitro Fertilization and Embryo Transfer. Huang, Michael; Cham, Elaine M.; Eppes, Carey S.; Gerber, Susan E.; Reed, Kurt D.; Ernst, Linda M. // Pediatric & Developmental Pathology;Mar/Apr2012, Vol. 15 Issue 2, p127 

    Intrauterine infection with non- albicans Candida species is rare but can be catastrophic to the fetus. A subset of intrauterine infections with non- albicans Candida species has occurred in women who have undergone in vitro fertilization and embryo transfer (IVF-ET). We report a case of a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics